All Outputs (4)

Caffeine exposure induces browning features in adipose tissue in vitro and in vivo (2019)
Journal Article
Velickovic, K., Wayne, D., Lugo Leija, H. A., Bloor, I., Morris, D. E., Law, J., Budge, H., Sacks, H., Symonds, M. E., & Sottile, V. (2019). Caffeine exposure induces browning features in adipose tissue in vitro and in vivo. Scientific Reports, 9(1), Article 9104. https://doi.org/10.1038/s41598-019-45540-1

Brown adipose tissue (BAT) is able to rapidly generate heat and metabolise macronutrients, such as glucose and lipids, through activation of mitochondrial uncoupling protein 1 (UCP1). Diet can modulate UCP1 function but the capacity of individual nut... Read More about Caffeine exposure induces browning features in adipose tissue in vitro and in vivo.

Interscapular and Perivascular Brown Adipose Tissue Respond Differently to a Short-Term High-Fat Diet (2019)
Journal Article
Aldiss, P., Lewis, J., Boocock, D., Miles, A., Bloor, I., Ebling, F., Budge, H., & Symonds, M. (2019). Interscapular and Perivascular Brown Adipose Tissue Respond Differently to a Short-Term High-Fat Diet. Nutrients, 11(5), Article 1065. https://doi.org/10.3390/nu11051065

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. Brown adipose tissue (BAT) function may depend on its anatomical location and developmental origin. Interscapular BAT (iBAT) regulates acute macronutrient metabolism, whilst perivascular BAT (... Read More about Interscapular and Perivascular Brown Adipose Tissue Respond Differently to a Short-Term High-Fat Diet.

Sexual dimorphism of brown adipose tissue function (2019)
Journal Article
Robinson, L. J., Law, J., Astle, V., Gutiérrez García, M., Ohja, S., Symonds, M. E., Pitchford, N., & Budge, H. (2019). Sexual dimorphism of brown adipose tissue function. Journal of Pediatrics, 210, 166-172.e1. https://doi.org/10.1016/j.jpeds.2019.03.003

Objective
To determine whether brown adipose tissue (BAT) activity in school-age children differs between the sexes and to explore the impact of dietary intake, sedentary behavior, and picky/fussy eating.

Study design
Children aged 8.5-11.8 year... Read More about Sexual dimorphism of brown adipose tissue function.

Housing temperature modulates the impact of diet-induced rise in fat mass on adipose tissue before and during pregnancy in rats (2019)
Journal Article
Albustanji, L., Perez, G. S., Alharethi, E., Aldiss, P., Bloor, I., Barreto-Medeiros, J. M., Budge, H., Symonds, M. E., & Dellschaft, N. (2019). Housing temperature modulates the impact of diet-induced rise in fat mass on adipose tissue before and during pregnancy in rats. Frontiers in Physiology, 10, https://doi.org/10.3389/fphys.2019.00209

Aim: To investigate whether housing temperature influences rat adiposity, and the extent it is modified by diet and/or pregnancy. Housing temperature impacts on brown adipose tissue, that possess a unique uncoupling protein (UCP) 1, which, when activ... Read More about Housing temperature modulates the impact of diet-induced rise in fat mass on adipose tissue before and during pregnancy in rats.