All Outputs (2)

The sphingosine 1‐phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus (2024)
Journal Article
Magalhães, D. M., Stewart, N. A., Mampay, M., Rolle, S. O., Hall, C. M., Moeendarbary, E., …Sheridan, G. K. (in press). The sphingosine 1‐phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus. Journal of Neurochemistry, https://doi.org/10.1111/jnc.16073

The small‐molecule drug, FTY720 (fingolimod), is a synthetic sphingosine 1‐phosphate (S1P) analogue currently used to treat relapsing–remitting multiple sclerosis in both adults and children. FTY720 can cross the blood–brain barrier (BBB) and, over t... Read More about The sphingosine 1‐phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus.

Age-related impact of social isolation in mice: Young vs middle-aged (2024)
Journal Article
Magalhães, D. M., Mampay, M., Sebastião, A. M., Sheridan, G. K., & Valente, C. A. (2024). Age-related impact of social isolation in mice: Young vs middle-aged. Neurochemistry International, 174, Article 105678. https://doi.org/10.1016/j.neuint.2024.105678

Social isolation is a chronic mild stressor and a significant risk factor for mental health disorders. Herein we explored the impact of social isolation on depression- and anxiety-like behaviours, as well as spatial memory impairments, in middle-aged... Read More about Age-related impact of social isolation in mice: Young vs middle-aged.