All Outputs (3)

Poroelastic osmoregulation of living cell volume (2021)
Journal Article
Esteki, M. H., Malandrino, A., Alemrajabi, A. A., Sheridan, G. K., Charras, G., & Moeendarbary, E. (2021). Poroelastic osmoregulation of living cell volume. iScience, 24(12), Article 103482. https://doi.org/10.1016/j.isci.2021.103482

Cells maintain their volume through fine intracellular osmolarity regulation. Osmotic challenges drive fluid into or out of cells causing swelling or shrinkage, respectively. The dynamics of cell volume changes depending on the rheology of the cellul... Read More about Poroelastic osmoregulation of living cell volume.

Tumour brain: pre‐treatment cognitive and affective disorders caused by peripheral cancers (2021)
Journal Article
Mampay, M., Flint, M. S., & Sheridan, G. K. (2021). Tumour brain: pre‐treatment cognitive and affective disorders caused by peripheral cancers. British Journal of Pharmacology, 178(19), 3977-3996. https://doi.org/10.1111/bph.15571

People that develop extracranial cancers often display co-morbid neurological disorders, such as anxiety, depression and cognitive impairment, even before commencement of chemotherapy. This suggests bidirectional crosstalk between non-CNS tumours and... Read More about Tumour brain: pre‐treatment cognitive and affective disorders caused by peripheral cancers.

Extracellular Vesicles and Intercellular Communication in the Central Nervous System (2021)
Journal Article
Lizarraga‐Valderrama, L. R., & Sheridan, G. K. (2021). Extracellular Vesicles and Intercellular Communication in the Central Nervous System. FEBS Letters, 595(10), 1391-1410. https://doi.org/10.1002/1873-3468.14074

Neurons and glial cells of the central nervous system (CNS) release extracellular vesicles (EVs) to the interstitial fluid of the brain and spinal cord parenchyma. EVs contain proteins, nucleic acids and lipids that can be taken up by, and modulate t... Read More about Extracellular Vesicles and Intercellular Communication in the Central Nervous System.