All Outputs (3)

Study on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane-Impermeable Antibiotics (2021)
Journal Article
Catania, R., Mastrotto, F., Moore, C. J., Bosquillon, C., Falcone, F. H., Huett, A., Mantovani, G., & Stolnik, S. (2021). Study on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane-Impermeable Antibiotics. Advanced Therapeutics, 4(12), Article 2100168. https://doi.org/10.1002/adtp.202100168

Water-soluble antibiotics are largely excluded from therapy of intracellular infections, such as Shigella spp., Listeria spp., or Salmonella spp., due to their inability to permeate mammalian cell membrane. Here, the authors study if targeting offers... Read More about Study on Significance of Receptor Targeting in Killing of Intracellular Bacteria with Membrane-Impermeable Antibiotics.

PEG-polyaminoacid based micelles for controlled release of doxorubicin: Rational design, safety and efficacy study (2021)
Journal Article
Brunato, S., Mastrotto, F., Bellato, F., Bastiancich, C., Travanut, A., Garofalo, M., Mantovani, G., Alexander, C., Preat, V., Salmaso, S., & Caliceti, P. (2021). PEG-polyaminoacid based micelles for controlled release of doxorubicin: Rational design, safety and efficacy study. Journal of Controlled Release, 335, 21-37. https://doi.org/10.1016/j.jconrel.2021.05.010

A library of amphiphilic monomethoxypolyethylene glycol (mPEG) terminating polyaminoacid co-polymers able to self-assemble into colloidal systems was screened for the delivery and controlled release of doxorubicin (Doxo). mPEG-Glu/Leu random co-polym... Read More about PEG-polyaminoacid based micelles for controlled release of doxorubicin: Rational design, safety and efficacy study.

Combining Inducible Lectin Expression and Magnetic Glyconanoparticles for the Selective Isolation of Bacteria from Mixed Populations (2021)
Journal Article
Petch, J. E., Gurnani, P., Yilmaz, G., Mastrotto, F., Alexander, C., Heeb, S., Cámara, M., & Mantovani, G. (2021). Combining Inducible Lectin Expression and Magnetic Glyconanoparticles for the Selective Isolation of Bacteria from Mixed Populations. ACS Applied Materials and Interfaces, 13(16), 19230-19243. https://doi.org/10.1021/acsami.1c00907

The selective isolation of bacteria from mixed populations has been investigated in varied applications ranging from differential pathogen identification in medical diagnostics and food safety to the monitoring of microbial stress dynamics in industr... Read More about Combining Inducible Lectin Expression and Magnetic Glyconanoparticles for the Selective Isolation of Bacteria from Mixed Populations.