Skip to main content

Research Repository

Advanced Search

All Outputs (46)

Association between UK assistance dogs’ British Veterinary Association/Kennel Club hip scores and their risk of clinical hip disease in later life (2025)
Journal Article
Lewis, T., England, G., & Moxon, R. (2025). Association between UK assistance dogs’ British Veterinary Association/Kennel Club hip scores and their risk of clinical hip disease in later life. Veterinary Record, 196(7), e5224. https://doi.org/10.1002/vetr.5224

Background: Screening schemes for hip dysplasia have long been used to guide breeding. However, the risks of clinical disease for dogs with high versus low scores are not well documented. Methods: Longitudinal data were used to quantify the risk of c... Read More about Association between UK assistance dogs’ British Veterinary Association/Kennel Club hip scores and their risk of clinical hip disease in later life.

Experiences of End-of-Life Decision-Making in Equine Veterinary and Charity Teams (2025)
Journal Article
Cameron, A., Geldard, M., Mair, T., England, G., Burford, J., Freeman, S., Pollock, K., & Wilson, E. (2025). Experiences of End-of-Life Decision-Making in Equine Veterinary and Charity Teams. Animals, 15(5), Article 678. https://doi.org/10.3390/ani15050678

Veterinary and charity teams are frequently involved in equine end-of-life decisions. These can cause ethical dilemmas and emotional burdens and complicate communication with owners. Semi-structured focus groups explored experiences of making decisio... Read More about Experiences of End-of-Life Decision-Making in Equine Veterinary and Charity Teams.

A Prospective Study Investigating the Health Outcomes of Bitches Neutered Prepubertally or Post-Pubertally (2025)
Journal Article
Moxon, R., Freeman, S. L., Payne, R. M., Corr, S., & England, G. C. W. (2025). A Prospective Study Investigating the Health Outcomes of Bitches Neutered Prepubertally or Post-Pubertally. Animals, 15(2), Article 167. https://doi.org/10.3390/ani15020167

There are scant studies of associations between the pubertal status at neutering and subsequent health outcomes of female dogs. This study examined health data for Labrador and Golden Retriever crossbreed bitches neutered by ovariohysterectomy either... Read More about A Prospective Study Investigating the Health Outcomes of Bitches Neutered Prepubertally or Post-Pubertally.

Effect of neutering timing in relation to puberty on health in the female dog–a scoping review (2024)
Journal Article
Moxon, R., England, G. C., Payne, R., Corr, S. A., & Freeman, S. L. (2024). Effect of neutering timing in relation to puberty on health in the female dog–a scoping review. PLoS ONE, 19(10), Article e0311779. https://doi.org/10.1371/journal.pone.0311779

Background: Effects of neutering on bitch health have been reported, and are suggested to relate to bitch age at the time of neutering for some diseases. However, variation between published studies in terms of study populations and methodologies mak... Read More about Effect of neutering timing in relation to puberty on health in the female dog–a scoping review.

UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic (2024)
Journal Article
Burrell, K. L., Burford, J. H., England, G. C., & Freeman, S. L. (2024). UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic. Equine Veterinary Journal, https://doi.org/10.1111/evj.14124

Background: The survival of horses diagnosed with critical colic (requiring referral or euthanasia) relies on rapid and effective decision-making by the owner and veterinary practitioner. Objectives: To explore UK horse owners' and veterinary practit... Read More about UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic.

Horse owners' and veterinary practitioners' experiences of decision-making for critical cases of colic (2024)
Preprint / Working Paper
Freeman, S., Burrell, K., Burford, J., & England, G. Horse owners' and veterinary practitioners' experiences of decision-making for critical cases of colic

Background: The survival of horses diagnosed with critical colic relies on rapid and effective decision-making by owner and veterinary practitioner. Objectives: To explore horse owners’ and veterinary practitioners’ experiences of decision-making for... Read More about Horse owners' and veterinary practitioners' experiences of decision-making for critical cases of colic.

INSL3 Variation in Dogs Following Suppression and Recovery of the HPG Axis (2024)
Journal Article
Anand-Ivell, R., Coutinho, A. R., Dai, Y., England, G., Goericke-Pesch, S., & Ivell, R. (2024). INSL3 Variation in Dogs Following Suppression and Recovery of the HPG Axis. Animals, 14(5), Article 675. https://doi.org/10.3390/ani14050675

Insulin-like peptide 3 (INSL3) is a constitutive product of mature, adult-type Leydig cells of the testes and consequently in most mammals is an ideal biomarker with which to monitor pubertal development. A new heterologous time-resolved fluorescence... Read More about INSL3 Variation in Dogs Following Suppression and Recovery of the HPG Axis.

Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches (2023)
Journal Article
Moxon, R., Dutton Worsfold, R., Davis, J., Adams, W., & England, G. C. W. (2023). Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches. Veterinary Medicine and Science, https://doi.org/10.1002/vms3.1195

Objectives: To establish packed cell volume (PCV) ranges for non‐pregnant, pregnant and post‐partum bitches from day 10 of proestrus, investigating any relationship with parity and litter size. Methods: This prospective cohort study used 37 healthy b... Read More about Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches.

Use of human behaviour change models to investigate horse owner intention to adopt emergency colic recommendations (2023)
Journal Article
Lightfoot, K. L., Frost, E., Burford, J. H., England, G. C. W., & Freeman, S. L. (2024). Use of human behaviour change models to investigate horse owner intention to adopt emergency colic recommendations. Equine Veterinary Journal, 56(1), 147-158. https://doi.org/10.1111/evj.13955

Background
Behavioural models are widely used within human medicine to understand beliefs and intention associated with major health interventions.

Objectives
To investigate horse-owner beliefs and practices associated with emergency colic plann... Read More about Use of human behaviour change models to investigate horse owner intention to adopt emergency colic recommendations.

A Prospective Cohort Study Investigating the Impact of Neutering Bitches Prepubertally or Post-Pubertally on Physical Development (2023)
Journal Article
Moxon, R., Freeman, S. L., Payne, R., Godfrey-Hunt, J., Corr, S., & England, G. C. W. (2023). A Prospective Cohort Study Investigating the Impact of Neutering Bitches Prepubertally or Post-Pubertally on Physical Development. Animals, 13(9), Article 1431. https://doi.org/10.3390/ani13091431

No previous large prospective cohort studies have been identified that have investigated the impact of the surgical neutering of bitches before or after known puberty on their growth and physical development. This study was designed to examine the da... Read More about A Prospective Cohort Study Investigating the Impact of Neutering Bitches Prepubertally or Post-Pubertally on Physical Development.

A Prospective Cohort Study Investigating the Behavioural Development of Bitches in a Guide Dog Training Programme Neutered Prepubertally or Post-Pubertally (2022)
Journal Article
Moxon, R., Freeman, S., Payne, R., Corr, S., & England, G. C. W. (2022). A Prospective Cohort Study Investigating the Behavioural Development of Bitches in a Guide Dog Training Programme Neutered Prepubertally or Post-Pubertally. Frontiers in Veterinary Science, 9, Article 902775. https://doi.org/10.3389/fvets.2022.902775

There are few studies that investigate the effect of neutering bitches before or after puberty. The majority of current literature examining the impact of the timing of neutering on health and behaviour has used age rather than the onset of puberty a... Read More about A Prospective Cohort Study Investigating the Behavioural Development of Bitches in a Guide Dog Training Programme Neutered Prepubertally or Post-Pubertally.

Scoping review of end-of-life decision-making models used in dogs, cats and equids (2022)
Journal Article
Cameron, A., Pollock, K., Wilson, E., Burford, J., England, G., & Freeman, S. (2022). Scoping review of end-of-life decision-making models used in dogs, cats and equids. Veterinary Record, 191(4), Article e1730. https://doi.org/10.1002/vetr.1730

Background: End-of-life decisions for companion animals can be stressful for veterinarians and owners, and when delayed result in poor animal welfare. Delayed euthanasia has been identified as a particularly prominent issue for horses. This scoping r... Read More about Scoping review of end-of-life decision-making models used in dogs, cats and equids.

Comparative pathology of dog and human prostate cancer (2021)
Journal Article
Ryman-Tubb, T., Lothion-Roy, J. H., Metzler, V. M., Harris, A. E., Robinson, B. D., Rizvanov, A. A., Jeyapalan, J. N., James, V. H., England, G., Rutland, C. S., Persson, J. L., Kenner, L., Rubin, M. A., Mongan, N. P., & de Brot, S. (2022). Comparative pathology of dog and human prostate cancer. Veterinary Medicine and Science, 8(1), 110-120. https://doi.org/10.1002/vms3.642

Though relatively rare in dogs, prostate cancer (PCa) is the most common non-cutaneous cancer in men. Human and canine prostate glands share many functional, anatomical and physiological features. Due to these similarities, canine PCa has been propos... Read More about Comparative pathology of dog and human prostate cancer.

Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology (2021)
Journal Article
Sumner, R. N., Byers, A., Zhang, Z., Agerholm, J. S., Lindh, L., England, G. C. W., & Lea, R. G. (2021). Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology. Scientific Reports, 11, Article 7361. https://doi.org/10.1038/s41598-021-86805-y

In humans and dogs, a temporal decline in semen quality and increased incidence of testicular cancer is hypothesised to be associated with exposure to anthropogenic chemicals, particularly during fetal development. Human studies suggest that differen... Read More about Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology.

Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs (2021)
Journal Article
Spada, S., England, G. C. W., Vignoli, M., Carluccio, A., & Russo, M. (2021). Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs. Animals, 11(2), Article 559. https://doi.org/10.3390/ani11020559

Prostatic neoplasia (PN) occurs in 5–7% of dogs with prostatic disease, with castrated dogs having the same or higher prevalence when compared to intact dogs. Considering the promising results achieved by performing contrast-enhanced ultrasound (CEUS... Read More about Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs.

Cross‐sectional study of UK horse owner's purchase and euthanasia decision‐making for their horse (2021)
Journal Article
Clough, H., Roshier, M., England, G., Burford, J., & Freeman, S. (2021). Cross‐sectional study of UK horse owner's purchase and euthanasia decision‐making for their horse. Veterinary Record, 188(6), Article e56. https://doi.org/10.1002/vetr.56

Background: This cross-sectional study aimed to investigate factors affecting horse owners’ purchase and euthanasia decisions that had been identified in a qualitative study.
Methods: An online survey on horse owners’ purchase and euthanasia decisi... Read More about Cross‐sectional study of UK horse owner's purchase and euthanasia decision‐making for their horse.

Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis (2020)
Journal Article
England, G., Rijsselaere, T., Campbell, A., Moxon, R., & Freeman, S. (2021). Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis. Theriogenology, 159, 176-183. https://doi.org/10.1016/j.theriogenology.2020.10.013

In mammalian species there are significant physiological responses of the female reproductive tract to the deposition of sperm. These are particularly notable in species where sperm are deposited directly into the uterus, and function both to facilit... Read More about Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis.

Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic (2020)
Journal Article
Bowden, A., England, G. C. W., Brennan, M. L., Mair, T. S., Furness, W. A., Freeman, S. L., & Burford, J. H. (2020). Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic. Veterinary Record, 187(12), 492-492. https://doi.org/10.1136/vr.105881

Background: This study aimed to describe the presentation and outcomes of horses with signs of colic (abdominal pain) seen 'out-of-hours' in equine practice. Methods: This was a retrospective study of horses seen 'out-of-hours' with colic by two equi... Read More about Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic.

Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners (2020)
Journal Article
Boynova, P., Bowden, A., Boynova, P., England, G. C. W., Brennan, M. L., Mair, T. S., Furness, W. A., Freeman, S. L., & Burford, J. H. (2020). Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners. Veterinary Record, 187(10), 404-404. https://doi.org/10.1136/vr.105880

Background: The study aim was to describe conditions seen 'out-of-hours' in equine practice. Methods: This was a retrospective case series of first opinion 'out-of-hours' cases seen at two equine practices between 2011 and 2013. Data were retrieved o... Read More about Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners.