All Outputs (15)

A qualitative exploration into the experience of mindfulness in moderate-severe persistent depression (2025)
Journal Article
Sweeney, T., Nixon, E., Morriss, R., & Callaghan, P. (2025). A qualitative exploration into the experience of mindfulness in moderate-severe persistent depression. PLoS ONE, 20(6), Article e0323294. https://doi.org/10.1371/journal.pone.0323294

Depression is a common and growing mental health problem, with around 5% of the world’s population experiencing an episode of depression during their lifetime. Relapse rates are high, with around half experiencing more than one depressive episode and... Read More about A qualitative exploration into the experience of mindfulness in moderate-severe persistent depression.

Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial (2025)
Journal Article
Nixon, E., Patel, S., Patel, P., Roe, J., Nixon, N., Sweeney, T., Bernard, P., Strauss, C., Craven, M., Malins, S., Goodwin, R., Astill Wright, L., Guo, B., & Morriss, R. (2025). Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial. JMIR Research Protocols, 14, Article e67695. https://doi.org/10.2196/67695

Background:

Recently published guidelines by the National Institute for Health and Care Excellence (NICE) have recommended both mindfulness-based and stress-reduction approaches as effective preventative mental wellbeing interventions for healthca... Read More about Mindfulness-Based Cognitive Therapy-for Life (MBCT-L) versus Stress-Reduction Psychoeducation (SRP) for the improvement of mental wellbeing in healthcare and other public sector staff: Protocol for the ‘Well at Work’ randomised controlled trial.

Navigating the medical journey: Insights into medical students’ psychological wellbeing, coping, and personality (2025)
Journal Article
Hawsawi, A. A., Nixon, N., & Nixon, E. (2025). Navigating the medical journey: Insights into medical students’ psychological wellbeing, coping, and personality. PLoS ONE, 20(2), Article e0318399. https://doi.org/10.1371/journal.pone.0318399

Background and aims In recent years, increased awareness of the psychological wellbeing of healthcare professionals and students has become a pressing public health issue affecting care delivery. Medical students undergo rigorous training programs th... Read More about Navigating the medical journey: Insights into medical students’ psychological wellbeing, coping, and personality.

Mental health and resilience in young people on Saint Helena Island (2024)
Journal Article
Murphy, T. L., & Nixon, E. (2025). Mental health and resilience in young people on Saint Helena Island. Clinical Child Psychology and Psychiatry, 30(2), 264-278. https://doi.org/10.1177/13591045241284326

This study explored the mental health needs and strengths of young people (aged 11–18 years) living on the remote island of Saint Helena (SH). 24 young people and their carers completed standardised inventories assessing mental health and resilience,... Read More about Mental health and resilience in young people on Saint Helena Island.

Exploring access to support services for medical students: recommendations for enhancing wellbeing support (2024)
Journal Article
Hawsawi, A. A., Nixon, N., Stewart, E., & Nixon, E. (2024). Exploring access to support services for medical students: recommendations for enhancing wellbeing support. BMC Medical Education, 24, Article 671. https://doi.org/10.1186/s12909-024-05492-1

Background
Medical students have reported facing unique challenges in their academic journey that can have a significant impact on their mental health and wellbeing; therefore, their access to support services and wellbeing resources has been deemed... Read More about Exploring access to support services for medical students: recommendations for enhancing wellbeing support.

Self-help digital interventions targeted at improving psychological well-being in young people with perceived or clinically diagnosed reduced wellbeing: Systematic Review (2022)
Journal Article
Babbage, C. M., Jackson, G. M., Davies, E. B., & Nixon, E. (2022). Self-help digital interventions targeted at improving psychological well-being in young people with perceived or clinically diagnosed reduced wellbeing: Systematic Review. JMIR Mental Health, 9(8), Article e25716. https://doi.org/10.2196/25716

Psychometric Properties of the Five Facets Mindfulness Questionnaire in Moderate-to-Severe, Persistent Depression (2021)
Journal Article
Sweeney, T., Morriss, R., Nixon, E., Guo, B., & Callaghan, P. (2021). Psychometric Properties of the Five Facets Mindfulness Questionnaire in Moderate-to-Severe, Persistent Depression. Mindfulness, 12, 1009–1021. https://doi.org/10.1007/s12671-020-01573-6

Objectives
Mindfulness has been increasingly incorporated into modern psychotherapies and healthcare services. The importance of psychometrically quantifying the construct of mindfulness has become paramount. One of the most reliable and valid instr... Read More about Psychometric Properties of the Five Facets Mindfulness Questionnaire in Moderate-to-Severe, Persistent Depression.

The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome (2020)
Journal Article
Nixon, N., Guo, B., Garland, A., Kaylor-Hughes, C., Nixon, E., & Morriss, R. (2020). The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome. PLoS ONE, 15(10), Article e0241370. https://doi.org/10.1371/journal.pone.0241370

Background:
The 17-item Hamilton Depression Rating Scale (HDRS17) is used world-wide as an observer-rated measure of depression in randomised controlled trials (RCTs) despite continued uncertainty regarding its factor structure. This study investiga... Read More about The bi-factor structure of the 17-item Hamilton Depression Rating Scale in persistent major depression; dimensional measurement of outcome.

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Bouman, W. P., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background
Cross-sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgender... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: a prospective cohort study.

Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study (2020)
Journal Article
Aldridge, Z., Patel, S., Guo, B., Nixon, E., Pierre Bouman, W., Witcomb, G. L., & Arcelus, J. (2021). Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study. Andrology, 9(6), 1808-1816. https://doi.org/10.1111/andr.12884

Background

Cross‐sectional studies show that transgender people are more likely than cisgender people to experience depression and anxiety before Gender Affirming Hormone Treatment (GAHT). However, the effect of GAHT on mental health in transgende... Read More about Long term effect of gender affirming hormone treatment on depression and anxiety symptoms in transgender people: A prospective cohort study.

Tic frequency and behavioural measures of cognitive control are improved in individuals with Tourette syndrome by aerobic exercise training (2020)
Journal Article
Jackson, G. M., Nixon, E., & Jackson, S. R. (2020). Tic frequency and behavioural measures of cognitive control are improved in individuals with Tourette syndrome by aerobic exercise training. Cortex, 129, 188-198. https://doi.org/10.1016/j.cortex.2020.01.029

Previous observations of improvements in cognition in typically developing children following moderate to vigorous exercise (e.g., Budde, Voelcker-Rehage, Pietrabyk-Kendziorra, Ribeiro, & Tidow, 2008; Hillman et al., 2009) have led to increased inter... Read More about Tic frequency and behavioural measures of cognitive control are improved in individuals with Tourette syndrome by aerobic exercise training.

Effects of single session cathodal transcranial direct current stimulation on tic symptoms in Tourette's syndrome (2019)
Journal Article
Dyke, K., Jackson, G. M., Nixon, E., & Jackson, S. R. (2019). Effects of single session cathodal transcranial direct current stimulation on tic symptoms in Tourette's syndrome. Experimental Brain Research, 237(11), 2853–2863. https://doi.org/10.1007/s00221-019-05637-5

Tourette syndrome is a neurodevelopmental disorder characterised by motor and phonic tics. For some, tics can be managed using medication and/or forms of behavioural therapy, however, adverse side effects and access to specialist resources can be bar... Read More about Effects of single session cathodal transcranial direct current stimulation on tic symptoms in Tourette's syndrome.

Desired features of a digital technology tool for self-management of well-being in a nonclinical sample of young people: qualitative study (2018)
Journal Article
Babbage, C., Jackson, G., & Nixon, E. (2018). Desired features of a digital technology tool for self-management of well-being in a nonclinical sample of young people: qualitative study. JMIR Mental Health, 5(4), Article e10067. https://doi.org/10.2196/10067

Background: Adaptive coping behaviours can improve wellbeing for young people experiencing life stressors while maladaptive coping can increase vulnerability to mental health problems in youth and into adulthood. Young people could potentially benefi... Read More about Desired features of a digital technology tool for self-management of well-being in a nonclinical sample of young people: qualitative study.

A comparison of mental health symptomatology and levels of social support in young treatment seeking transgender individuals who identify as binary and non-binary (2018)
Journal Article
Thorne, N., Witcomb, G. L., Nieder, T., Nixon, E., Yip, A., & Arcelus, J. (2019). A comparison of mental health symptomatology and levels of social support in young treatment seeking transgender individuals who identify as binary and non-binary. International Journal of Transgenderism, 20(2-3), 241-250. https://doi.org/10.1080/15532739.2018.1452660

Background: Previous research has consistently reported high rates of mental health symptomatology and lower social support in young treatment seeking transgender individuals. However, these studies have failed to distinguish between transgender peop... Read More about A comparison of mental health symptomatology and levels of social support in young treatment seeking transgender individuals who identify as binary and non-binary.

Biological vulnerability to depression: Linked structural and functional brain network findings (2014)
Journal Article
Worwood, G., Nixon, E., Palaniyappan, L., Nixon, N. L., Liddle, P. F., Nixon, N. L., Liddle, P., Nixon, E., Worwood, G., Liotti, M., & Palaniyappan, L. (2014). Biological vulnerability to depression: Linked structural and functional brain network findings. British Journal of Psychiatry, 204(4), 283-289. https://doi.org/10.1192/bjp.bp.113.129965

Background: Patients in recovery following episodes of major depressive disorder (MDD) remain highly vulnerable to future recurrence. Although psychological determinants of this risk are well established, little is known about associated biological m... Read More about Biological vulnerability to depression: Linked structural and functional brain network findings.