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Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review (2021)
Journal Article
Ljungqvist, O., de Boer, H. D., Balfour, A., Fawcett, W. J., Lobo, D. N., Nelson, G., Scott, M. J., Wainwright, T. W., & Demartines, N. (2021). Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review. JAMA Surgery, 156(8), 775-784. https://doi.org/10.1001/jamasurg.2021.0586

Importance: Enhanced Recovery After Surgery (ERAS) is a global surgical quality improvement initiative now firmly entrenched within the field of perioperative care. Although ERAS is associated with significant clinical outcome improvements and cost... Read More about Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review.

ESPEN practical guideline: Clinical nutrition in surgery (2021)
Journal Article
Weimann, A., Braga, M., Carli, F., Higashiguchi, T., Hübner, M., Klek, S., Laviano, A., Ljungqvist, O., Lobo, D. N., Martindale, R. G., Waitzberg, D., Bischoff, S. C., & Singer, P. (2021). ESPEN practical guideline: Clinical nutrition in surgery. Clinical Nutrition, 40(7), 4745-4761. https://doi.org/10.1016/j.clnu.2021.03.031

Early oral feeding is the preferred mode of nutrition for surgical patients. Avoidance of any nutritional therapy bears the risk of underfeeding during the postoperative course after major surgery. Considering that malnutrition and underfeeding are r... Read More about ESPEN practical guideline: Clinical nutrition in surgery.

Opioid prescription at postoperative discharge: a retrospective observational cohort study (2021)
Journal Article
Daliya, P., Adiamah, A., Roslan, F., Theophilidou, E., Knaggs, R., Levy, N., & Lobo, D. (2021). Opioid prescription at postoperative discharge: a retrospective observational cohort study. Anaesthesia, 76(10), 1367-1376. https://doi.org/10.1111/anae.15460

Opioid misuse is now considered a major public health epidemic in North America, with substantial social and financial consequences. As well as socio-economic and commercial drivers, modifiable risk-factors that have resulted in this crisis have been... Read More about Opioid prescription at postoperative discharge: a retrospective observational cohort study.

Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization (2021)
Journal Article
Peden, C. J., Aggarwal, G., Aitken, R. J., Anderson, I. D., Bang Foss, N., Cooper, Z., Dhesi, J. K., French, W. B., Grant, M. C., Hammarqvist, F., Hare, S. P., Havens, J. M., Holena, D. N., Hübner, M., Kim, J. S., Lees, N. P., Ljungqvist, O., Lobo, D. N., Mohseni, S., Ordoñez, C. A., …Scott, M. (2021). Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization. World Journal of Surgery, 45, 1272–1290. https://doi.org/10.1007/s00268-021-05994-9

Background
Enhanced Recovery After Surgery (ERAS) protocols reduce length of stay, complications and costs fora large number of elective surgical procedures. A similar, structured approach appears to improve outcomes, including mortality, for patien... Read More about Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization.

Patient-centric goal-oriented perioperative care (2021)
Journal Article
Roberts, G. P., Levy, N., & Lobo, D. N. (2021). Patient-centric goal-oriented perioperative care. British Journal of Anaesthesia, 126(3), 559-564. https://doi.org/10.1016/j.bja.2020.12.004

Anaesthetists and surgeons largely focus on quantifiable postoperative outcome measures as a means for improving the quality of patient care. However, whilst traditional measures, such as postoperative morbidity and mortality, are useful and relative... Read More about Patient-centric goal-oriented perioperative care.

The centenary of the Harris–Benedict equations: How to assess energy requirements best? Recommendations from the ESPEN expert group (2020)
Journal Article
Bendavid, I., Lobo, D. N., Barazzoni, R., Cederholm, T., Coëffier, M., Schueren, M. D. V. D., Fontaine, E., Hiesmayr, M., Laviano, A., Pichard, C., & Singer, P. (2021). The centenary of the Harris–Benedict equations: How to assess energy requirements best? Recommendations from the ESPEN expert group. Clinical Nutrition, 40(3), 690-701. https://doi.org/10.1016/j.clnu.2020.11.012

Background & aims: The year 2019 marked the centenary of the publication of the Harris and Benedict equations for estimation of energy expenditure. In October 2019 a Scientific Symposium was organized by the European Society for Clinical Nutrition an... Read More about The centenary of the Harris–Benedict equations: How to assess energy requirements best? Recommendations from the ESPEN expert group.

Enhanced recovery after surgery: Current status and future progress (2020)
Journal Article
Rollins, K. E., Lobo, D. N., & Joshi, G. P. (2021). Enhanced recovery after surgery: Current status and future progress. Best Practice and Research: Clinical Anaesthesiology, 35(4), 479-489. https://doi.org/10.1016/j.bpa.2020.10.001

Enhanced Recovery After Surgery (ERAS) pathways were first introduced almost a quarter of a century ago and represent a paradigm shift in perioperative care that reduced postoperative complications and hospital length of stay, improved postoperative... Read More about Enhanced recovery after surgery: Current status and future progress.

An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients (2020)
Journal Article
Levy, N., Quinlan, J., El‐Boghdadly, K., Fawcett, W. J., Agarwal, V., Bastable, R. B., Cox, F. J., de Boer, H. D., Dowdy, S. C., Hattingh, K., Knaggs, R. D., Mariano, E. R., Pelosi, P., Scott, M. J., Lobo, D. N., & Macintyre, P. E. (2020). An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients. Anaesthesia, 76(4), 520-536. https://doi.org/10.1111/anae.15262

This international multidisciplinary consensus statement was developed to provide balanced guidance on the safe peri‐operative use of opioids in adults. An international panel of healthcare professionals evaluated the literature relating to postopera... Read More about An international multidisciplinary consensus statement on the prevention of opioid-related harm in adult surgical patients.

Turning ‘waiting lists’ for elective surgery into ‘preparation lists’ (2020)
Journal Article
Levy, N., Selwyn, D., & Lobo, D. (2021). Turning ‘waiting lists’ for elective surgery into ‘preparation lists’. British Journal of Anaesthesia, 126(1), 1-5. https://doi.org/10.1016/j.bja.2020.08.021

Waiting lists for surgery are an integral part of the UK National Health Service (NHS); they are used as a construct to ration surgery and to reduce costs, whilst simultaneously attempting to distribute limited health resources in an equitable manner... Read More about Turning ‘waiting lists’ for elective surgery into ‘preparation lists’.

Fasting and surgery timing (FaST) audit (2020)
Journal Article
El-Sharkawy, A. M., Daliya, P., Lewis-Lloyd, C., Adiamah, A., Malcolm, F. L., Boyd-Carson, H., Couch, D., Herrod, P. J., Hossain, T., Couch, J., Sarmah, P. B., Sian, T. S., Lobo, D. N., Anjum, S., Aghanenu, O., Barlow, S., Chukwuemeka, W., Couch, J., Daliya, P., Daud, H., …Wolff, J. (2021). Fasting and surgery timing (FaST) audit. Clinical Nutrition, 40(3), 1405-1412. https://doi.org/10.1016/j.clnu.2020.08.033

Background & aims

International guidance advocates the avoidance of prolonged preoperative fasting due to its negative impact on perioperative hydration. This study aimed to assess the adherence to these guidelines for fasting in patients undergoi... Read More about Fasting and surgery timing (FaST) audit.

Major elective abdominal surgery acutely impairs lower limb muscle pyruvate dehydrogenase complex activity and mitochondrial function (2020)
Journal Article
Atkins, R., Constantin-Teodosiu, D., Varadhan, K. K., Constantin, D., Lobo, D. N., & Greenhaff, P. L. (2021). Major elective abdominal surgery acutely impairs lower limb muscle pyruvate dehydrogenase complex activity and mitochondrial function. Clinical Nutrition, 40(3), 1046-1051. https://doi.org/10.1016/j.clnu.2020.07.006

© 2020 The Author(s) Background & aims: This post hoc study aimed to determine whether major elective abdominal surgery had any acute impact on mitochondrial pyruvate dehydrogenase complex (PDC) activity and maximal mitochondrial ATP production rates... Read More about Major elective abdominal surgery acutely impairs lower limb muscle pyruvate dehydrogenase complex activity and mitochondrial function.

Hypertriglyceridaemia as a risk factor for critical care admission in acute pancreatitis: A prospective study (2020)
Journal Article
Adiamah, A., Kushairi, A., Tumulty, S., Na, Y., Crook, M., Brooks, A. J., Lobo, D. N., & Nottingham University Hospitals Hepatopancreaticobiliary Team. (2020). Hypertriglyceridaemia as a risk factor for critical care admission in acute pancreatitis: A prospective study. Clinical Nutrition ESPEN, 39, 227-233. https://doi.org/10.1016/j.clnesp.2020.06.008

Background and aims
Hypertriglyceridaemia is both a primary cause of acute pancreatitis and an epiphenomenon. This study aimed to define the associations between hypertriglyceridaemia and clinical outcomes in patients admitted with acute pancreatiti... Read More about Hypertriglyceridaemia as a risk factor for critical care admission in acute pancreatitis: A prospective study.

Perioperative nutrition: Recommendations from the ESPEN expert group (2020)
Journal Article
Lobo, D. N., Gianotti, L., Adiamah, A., Barazzoni, R., Deutz, N., Dhatariya, K., Greenhaff, P. L., Hiesmayr, M., Jakobsen, D., Klek, S., Krznaric, Z., Ljungqvist, O., McMillan, D., Rollins, K., Sekeljic, M., Skipworth, R., Stanga, Z., Stockley, A., Stockley, R., & Weimann, A. (2020). Perioperative nutrition: Recommendations from the ESPEN expert group. Clinical Nutrition, 39(11), 3211-3227. https://doi.org/10.1016/j.clnu.2020.03.038

© 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism Background & aims: Malnutrition has been recognized as a major risk factor for adverse postoperative outcomes. The ESPEN Symposium on perioperative nutrition was held in N... Read More about Perioperative nutrition: Recommendations from the ESPEN expert group.

The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorectal surgery: A meta-analysis of randomised controlled trials (2020)
Journal Article
Rollins, K. E., Javanmard-Emamghissi, H., Scott, M. J., & Lobo, D. N. (2020). The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorectal surgery: A meta-analysis of randomised controlled trials. European Journal of Anaesthesiology, 37(8), 659-670. https://doi.org/10.1097/eja.0000000000001165

BACKGROUND
There has recently been increasing interest in the use of peri-operative intravenous lidocaine (IVL) due to its analgesic, anti-inflammatory and opioid-sparing effects. However, these potential benefits are not well established in electi... Read More about The impact of peri-operative intravenous lidocaine on postoperative outcome after elective colorectal surgery: A meta-analysis of randomised controlled trials.