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All Outputs (18)

Current Issues in the Use of Opioids for the Management of Postoperative Pain: A Review (2021)
Journal Article
Macintyre, P. E., Quinlan, J., Levy, N., & Lobo, D. N. (2022). Current Issues in the Use of Opioids for the Management of Postoperative Pain: A Review. JAMA Surgery, 157(2), 158-166. https://doi.org/10.1001/jamasurg.2021.6210

Importance: Uncontrolled and indiscriminate prescribing of opioids has led to an opioid crisis that started in North America and spread throughout high-income countries. The aim of this narrative review was to explore some of the current issues surro... Read More about Current Issues in the Use of Opioids for the Management of Postoperative Pain: A Review.

The importance of protein sources to support muscle anabolism in cancer: An expert group opinion (2021)
Journal Article
Ford, K. L., Arends, J., Atherton, P. J., Engelen, M. P., Gonçalves, T. J., Laviano, A., …Prado, C. M. (2022). The importance of protein sources to support muscle anabolism in cancer: An expert group opinion. Clinical Nutrition, 41(1), 192-201. https://doi.org/10.1016/j.clnu.2021.11.032

This opinion paper presents a short review of the potential impact of protein on muscle anabolism in cancer, which is associated with better patient outcomes. Protein source is a topic of interest for patients and clinicians, partly due to recent emp... Read More about The importance of protein sources to support muscle anabolism in cancer: An expert group opinion.

Bowel Preparation for Colorectal Surgery: Have All Questions Been Answered? (2021)
Journal Article
Ljungqvist, O., & Lobo, D. N. (2021). Bowel Preparation for Colorectal Surgery: Have All Questions Been Answered?. JAMA Surgery, 157(1), 41-42. https://doi.org/10.1001/jamasurg.2021.5273

Rosenberg and colleagues1 first proposed the use of nonabsorbable oral antibiotic preparation (OAB) for colorectal surgery in 1971. In a randomized clinical trial, they demonstrated a reduction in surgical site infection and anastomotic leak rates af... Read More about Bowel Preparation for Colorectal Surgery: Have All Questions Been Answered?.

Incidence and treatment of splanchnic vein thrombosis in patients with acute pancreatitis: A systematic review and meta-analysis (2021)
Journal Article
Anis, F. S., Adiamah, A., Lobo, D. N., & Sanyal, S. (2022). Incidence and treatment of splanchnic vein thrombosis in patients with acute pancreatitis: A systematic review and meta-analysis. Journal of Gastroenterology and Hepatology, 37(3), 446-454. https://doi.org/10.1111/jgh.15711

Background and Aim: This meta-analysis aimed to estimate the incidence of splanchnic vein thrombosis (SVT) in patients with acute pancreatitis and assess the effects of therapeutic anticoagulation. Methods: Systematic searches of the Medline, Embase,... Read More about Incidence and treatment of splanchnic vein thrombosis in patients with acute pancreatitis: A systematic review and meta-analysis.

Management of disease-related malnutrition for patients being treated in hospital (2021)
Journal Article
Schuetz, P., Seres, D., Lobo, D. N., Gomes, F., Kaegi-Braun, N., & Stanga, Z. (2021). Management of disease-related malnutrition for patients being treated in hospital. Lancet, 398(10314), 1927-1938. https://doi.org/10.1016/S0140-6736%2821%2901451-3

Disease-related malnutrition in adult patients who have been admitted to hospital is a syndrome associated with substantially increased morbidity, disability, short-term and long-term mortality, impaired recovery from illness, and cost of care. There... Read More about Management of disease-related malnutrition for patients being treated in hospital.

Immunohistochemical inflammation in histologically normal appendices in patients with right iliac fossa pain (2021)
Journal Article
Psaltis, E., Zaitoun, A. M., Neal, K. R., & Lobo, D. N. (2021). Immunohistochemical inflammation in histologically normal appendices in patients with right iliac fossa pain. World Journal of Surgery, 45(12), 3592-3602. https://doi.org/10.1007/s00268-021-06288-w

Background Histologically normal appendices resected for right iliac fossa pain in children demonstrate immunohistochemical markers of inflammation. We aimed to establish if subclinical inflammation was present in histologically normal appendices re... Read More about Immunohistochemical inflammation in histologically normal appendices in patients with right iliac fossa pain.

Publication Rates, Ethnic and Sex Disparities in UK and Ireland Surgical Research Prize Presentations: An Analysis of Data From the Moynihan and Patey Prizes From 2000 to 2020 (2021)
Journal Article
Seehra, J. K., Lewis-Lloyd, C., Koh, A., Theophilidou, E., Daliya, P., Adiamah, A., & Lobo, D. N. (2021). Publication Rates, Ethnic and Sex Disparities in UK and Ireland Surgical Research Prize Presentations: An Analysis of Data From the Moynihan and Patey Prizes From 2000 to 2020. World Journal of Surgery, 45(11), 3266-3277. https://doi.org/10.1007/s00268-021-06268-0

Background: Presentation at academic conferences is an important marker of research productivity. However, not all accepted abstracts progress to full publication, and there is anecdotal evidence suggesting an imbalance in sex and ethnicity amongst p... Read More about Publication Rates, Ethnic and Sex Disparities in UK and Ireland Surgical Research Prize Presentations: An Analysis of Data From the Moynihan and Patey Prizes From 2000 to 2020.

Perioperative Opioids - Reclaiming Lost Ground (2021)
Journal Article
Fawcett, W. J., Ljungqvist, O., & Lobo, D. N. (2021). Perioperative Opioids - Reclaiming Lost Ground. JAMA Surgery, 156(11), 997-998. https://doi.org/10.1001/jamasurg.2021.2858

Opium (poppy tears) has been in use since 3400 BCE, with historical writings recording its sedative, euphoric, and analgesic properties, but it was not until the 19th century that morphine was isolated, paving the way for its therapeutic use. The 20t... Read More about Perioperative Opioids - Reclaiming Lost Ground.

Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review (2021)
Journal Article
Ljungqvist, O., de Boer, H. D., Balfour, A., Fawcett, W. J., Lobo, D. N., Nelson, G., …Demartines, N. (2021). Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review. JAMA Surgery, 156(8), 775-784. https://doi.org/10.1001/jamasurg.2021.0586

Importance: Enhanced Recovery After Surgery (ERAS) is a global surgical quality improvement initiative now firmly entrenched within the field of perioperative care. Although ERAS is associated with significant clinical outcome improvements and cost... Read More about Opportunities and Challenges for the Next Phase of Enhanced Recovery After Surgery: A Review.

ESPEN practical guideline: Clinical nutrition in surgery (2021)
Journal Article
Weimann, A., Braga, M., Carli, F., Higashiguchi, T., Hübner, M., Klek, S., …Singer, P. (2021). ESPEN practical guideline: Clinical nutrition in surgery. Clinical Nutrition, 40(7), 4745-4761. https://doi.org/10.1016/j.clnu.2021.03.031

Early oral feeding is the preferred mode of nutrition for surgical patients. Avoidance of any nutritional therapy bears the risk of underfeeding during the postoperative course after major surgery. Considering that malnutrition and underfeeding are r... Read More about ESPEN practical guideline: Clinical nutrition in surgery.

Opioid prescription at postoperative discharge: a retrospective observational cohort study (2021)
Journal Article
Daliya, P., Adiamah, A., Roslan, F., Theophilidou, E., Knaggs, R., Levy, N., & Lobo, D. (2021). Opioid prescription at postoperative discharge: a retrospective observational cohort study. Anaesthesia, 76(10), 1367-1376. https://doi.org/10.1111/anae.15460

Opioid misuse is now considered a major public health epidemic in North America, with substantial social and financial consequences. As well as socio-economic and commercial drivers, modifiable risk-factors that have resulted in this crisis have been... Read More about Opioid prescription at postoperative discharge: a retrospective observational cohort study.

Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization (2021)
Journal Article
Peden, C. J., Aggarwal, G., Aitken, R. J., Anderson, I. D., Bang Foss, N., Cooper, Z., …Scott, M. (2021). Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization. World Journal of Surgery, 45, 1272–1290. https://doi.org/10.1007/s00268-021-05994-9

Background Enhanced Recovery After Surgery (ERAS) protocols reduce length of stay, complications and costs fora large number of elective surgical procedures. A similar, structured approach appears to improve outcomes, including mortality, for patien... Read More about Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization.

Patient-centric goal-oriented perioperative care (2021)
Journal Article
Roberts, G. P., Levy, N., & Lobo, D. N. (2021). Patient-centric goal-oriented perioperative care. British Journal of Anaesthesia, 126(3), 559-564. https://doi.org/10.1016/j.bja.2020.12.004

Anaesthetists and surgeons largely focus on quantifiable postoperative outcome measures as a means for improving the quality of patient care. However, whilst traditional measures, such as postoperative morbidity and mortality, are useful and relative... Read More about Patient-centric goal-oriented perioperative care.