Production and use of encapsidated RNA mimics as positive control reagents for SARS-CoV-2 RT-qPCR diagnostics
(2021)
Journal Article
Peyret, H., Groppelli, E., Clark, D., Eckersley, N., Planche, T., Ma, J., & Lomonossoff, G. P. (2022). Production and use of encapsidated RNA mimics as positive control reagents for SARS-CoV-2 RT-qPCR diagnostics. Journal of Virological Methods, 300, Article 114372. https://doi.org/10.1016/j.jviromet.2021.114372
The current gold standard technique for SARS-CoV-2 diagnostics is hydrolysis probe-based RT-qPCR. Reliable testing requires reliable control reagents to monitor the efficiency of RNA extraction, reverse transcription and PCR amplification. Here we de... Read More about Production and use of encapsidated RNA mimics as positive control reagents for SARS-CoV-2 RT-qPCR diagnostics.