All Outputs (3)

Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study (2024)
Journal Article
Azam, A. S., Tsang, Y., Thirlwall, J., Kimani, P. K., Sah, S., Gopalakrishnan, K., Boyd, C., Loughrey, M. B., Kelly, P. J., Boyle, D. P., Salto‐Tellez, M., Clark, D., Ellis, I. O., Ilyas, M., Rakha, E., Bickers, A., Roberts, I. S. D., Soares, M. F., Neil, D. A. H., Takyi, A., …Snead, D. R. J. (2024). Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study. Histopathology, 84(5), 847-862. https://doi.org/10.1111/his.15129

Aims: To conduct a definitive multicentre comparison of digital pathology (DP) with light microscopy (LM) for reporting histopathology slides including breast and bowel cancer screening samples.
Methods: A total of 2024 cases (608 breast, 607 GI, 6... Read More about Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study.

Age within schoolyear and attention-deficit hyperactivity disorder in Scotland and Wales (2022)
Journal Article
Fleming, M., Bandyopadhyay, A., Mclay, J. S., Clark, D., King, A., Mackay, D. F., Lyons, R. A., Sayal, K., Brophy, S., & Pell, J. P. (2022). Age within schoolyear and attention-deficit hyperactivity disorder in Scotland and Wales. BMC Public Health, 22(1), Article 1070. https://doi.org/10.1186/s12889-022-13453-w

Background
Previous studies suggest an association between age within schoolyear and attention-deficit hyperactivity disorder (ADHD). Scotland and Wales have different school entry cut-off dates (six months apart) and policies on holding back childr... Read More about Age within schoolyear and attention-deficit hyperactivity disorder in Scotland and Wales.

Production and use of encapsidated RNA mimics as positive control reagents for SARS-CoV-2 RT-qPCR diagnostics (2021)
Journal Article
Peyret, H., Groppelli, E., Clark, D., Eckersley, N., Planche, T., Ma, J., & Lomonossoff, G. P. (2022). Production and use of encapsidated RNA mimics as positive control reagents for SARS-CoV-2 RT-qPCR diagnostics. Journal of Virological Methods, 300, Article 114372. https://doi.org/10.1016/j.jviromet.2021.114372

The current gold standard technique for SARS-CoV-2 diagnostics is hydrolysis probe-based RT-qPCR. Reliable testing requires reliable control reagents to monitor the efficiency of RNA extraction, reverse transcription and PCR amplification. Here we de... Read More about Production and use of encapsidated RNA mimics as positive control reagents for SARS-CoV-2 RT-qPCR diagnostics.