All Outputs (4)

Assessing muscle protein synthesis rates in vivo in humans: the deuterated water (2H2O) method (2024)
Journal Article
Holwerda, A. M., Atherton, P. J., Smith, K., Wilkinson, D. J., Phillips, S. M., & van Loon, L. J. (2024). Assessing muscle protein synthesis rates in vivo in humans: the deuterated water (2H2O) method. Journal of Nutrition, 154(11), 3177-3189. https://doi.org/10.1016/j.tjnut.2024.09.012

Skeletal muscle tissue is in a constant state of turnover, with muscle tissue protein synthesis and breakdown rates ranging between 1-2 % across the day in vivo in humans. Muscle tissue remodeling is largely controlled by the up- and down-regulation... Read More about Assessing muscle protein synthesis rates in vivo in humans: the deuterated water (2H2O) method.

The metabolic effects of intermittent versus continuous feeding in critically ill patients (2023)
Journal Article
Wilkinson, D., Gallagher, I. J., McNelly, A., Bear, D. E., Hart, N., Montgomery, H. E., …Puthucheary, Z. A. (2023). The metabolic effects of intermittent versus continuous feeding in critically ill patients. Scientific Reports, 13(1), Article 19508. https://doi.org/10.1038/s41598-023-46490-5

Intermittent (or bolus) feeding regimens in critically ill patients have been of increasing interest to clinicians and scientists. Changes in amino acid, fat and carbohydrate metabolites over time might yet deliver other benefits (e.g. modulation of... Read More about The metabolic effects of intermittent versus continuous feeding in critically ill patients.

Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women (2023)
Journal Article
MALLINSON, J., WARDLE, S., O'LEARY, T., GREEVES, J., CEGIELSKI, J., BASS, J., …GREENHAFF, P. (2023). Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women. Scandinavian Journal of Medicine and Science in Sports, 33(12), 2470-2481. https://doi.org/10.1111/sms.14506

Studies examining the effect of protein (PRO) feeding on post resistance exercise (RE) muscle protein synthesis (MPS) have primarily been performed in men, and little evidence is available regarding the quantity of PRO required to maximally stimulate... Read More about Protein dose requirements to maximise skeletal muscle protein synthesis after repeated bouts of resistance exercise in young trained women.

Characterization of a Helicobacter pylori strain with high biofilm-forming ability (2023)
Journal Article
Wilkinson, D., Alsharaf, L., Thompson, S., Paulin, A., Takor, R., Zaitoun, A., Robinson, K., Thomas, J., McVicker, G., & Winter, J. (2023). Characterization of a Helicobacter pylori strain with high biofilm-forming ability. Journal of Medical Microbiology, 72(6), Article 001710. https://doi.org/10.1099/jmm.0.001710

Introduction. Helicobacter pylori is highly polymorphic, and some strains are much more likely to cause disease than others. Biofilm formation can help bacteria to survive antibiotic treatment, immune attack and other stresses, promoting persistent i... Read More about Characterization of a Helicobacter pylori strain with high biofilm-forming ability.