All Outputs (5)

A genomic toolkit for winged bean Psophocarpus tetragonolobus (2024)
Journal Article
Ho, W. K., Tanzi, A. S., Sang, F., Tsoutsoura, N., Shah, N., Moore, C., …Mayes, S. (2024). A genomic toolkit for winged bean Psophocarpus tetragonolobus. Nature Communications, 15(1), Article 1901. https://doi.org/10.1038/s41467-024-45048-x

A sustainable supply of plant protein is critical for future generations and needs to be achieved while reducing green house gas emissions from agriculture and increasing agricultural resilience in the face of climate volatility. Agricultural diversi... Read More about A genomic toolkit for winged bean Psophocarpus tetragonolobus.

Magnesium and calcium overaccumulate in the leaves of a schengen3 mutant of Brassica rapa (2021)
Journal Article
Alcock, T. D., Thomas, C. L., Ó Lochlainn, S., Pongrac, P., Wilson, M., Moore, C., …Broadley, M. R. (2021). Magnesium and calcium overaccumulate in the leaves of a schengen3 mutant of Brassica rapa. Plant Physiology, 186(3), 1616-1631. https://doi.org/10.1093/PLPHYS/KIAB150

Magnesium (Mg) and calcium (Ca) are essential mineral nutrients poorly supplied in many human food systems. In grazing livestock, Mg and Ca deficiencies are costly welfare issues. Here, we report a Brassica rapa loss-of-function schengen3 (sgn3) muta... Read More about Magnesium and calcium overaccumulate in the leaves of a schengen3 mutant of Brassica rapa.

Gfi1aa and Gfi1b set the pace for primitive erythroblast differentiation from hemangioblasts in the zebrafish embryo (2018)
Journal Article
Moore, C., Richens, J. L., Hough, Y., Ucanok, D., Malla, S., Sang, F., …Gering, M. (2018). Gfi1aa and Gfi1b set the pace for primitive erythroblast differentiation from hemangioblasts in the zebrafish embryo. Blood Advances, 2(20), 2589-2606. https://doi.org/10.1182/bloodadvances.2018020156

The transcriptional repressors Gfi1(a) and Gfi1b are epigenetic regulators with unique and overlapping roles in hematopoiesis. In different contexts, Gfi1 and Gfi1b restrict or promote cell proliferation, prevent apoptosis, influence cell fate decisi... Read More about Gfi1aa and Gfi1b set the pace for primitive erythroblast differentiation from hemangioblasts in the zebrafish embryo.

Tropomyosin 1: multiple roles in the developing heart and in the formation of congenital heart defects (2017)
Journal Article
England, J., Granados-Riveron, J. T., Polo-Parada, L., Kuriakose, D., Moore, C., Brook, J. D., …Loughna, S. (2017). Tropomyosin 1: multiple roles in the developing heart and in the formation of congenital heart defects. Journal of Molecular and Cellular Cardiology, 106, https://doi.org/10.1016/j.yjmcc.2017.03.006

Tropomyosin 1 (TPM1) is an essential sarcomeric component, stabilising the thin filament and facilitating actin's interaction with myosin. A number of sarcomeric proteins, such as alpha myosin heavy chain, play crucial roles in cardiac development. M... Read More about Tropomyosin 1: multiple roles in the developing heart and in the formation of congenital heart defects.

Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae (2016)
Journal Article
Willis, A. R., Moore, C., Mazon-Moya, M., Krokowski, S., Lambert, C., Till, R., …Sockett, R. E. (2016). Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae. Current Biology, 26(24), 3343-3351. https://doi.org/10.1016/j.cub.2016.09.067

Bdellovibrio bacteriovorus are predatory bacteria that invade and kill a range of Gram-negative bacterial pathogens in natural environments and in vitro [ 1 and 2]. In this study, we investigated Bdellovibrio as an injected, antibacterial treatment i... Read More about Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae.