Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism

Loos, Malte; Klampe, Birgit; Schulze, Thomas; Yin, Xiaoke; Theofilatos, Konstantinos; Ulmer, Bärbel Maria; Schulz, Carl; Behrens, Charlotta S; van Bergen, Tessa Diana; Adami, Eleonora; Maatz, Henrike; Schweizer, Michaela; Brodesser, Susanne; Skryabin, Boris V; Rozhdestvensky, Timofey S; Bodbin, Sara; Stathopoulou, Konstantina; Christ, Torsten; Denning, Chris; Hübner, Norbert; Mayr, Manuel; Cuello, Friederike; Eschenhagen, Thomas; Hansen, Arne

doi:10.1016/j.stemcr.2023.09.002

All Outputs (2)

‘Project period’: a workplace health promotion innovation in a higher education setting (2023)
Journal Article
Blake, H., Raniga, K., Yildirim, M., & Denning, C. (2024). ‘Project period’: a workplace health promotion innovation in a higher education setting. Perspectives in Public Health, 144(1), 5-8. https://doi.org/10.1177/17579139231185668

Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism (2023)
Journal Article
Loos, M., Klampe, B., Schulze, T., Yin, X., Theofilatos, K., Ulmer, B. M., …Hansen, A. (2023). Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism. Stem Cell Reports, 18(11), 2123-2137. https://doi.org/10.1016/j.stemcr.2023.09.002

Primary carnitine deficiency (PCD) is an autosomal recessive monogenic disorder caused by mutations in SLC22A5. This gene encodes for OCTN2, which transports the essential metabolite carnitine into the cell. PCD patients suffer from muscular weakness... Read More about Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism.