All Outputs (81)

Strategies to improve recruitment in mental health clinical trials: a scoping review (RE-MIND study) (2024)
Journal Article
Iflaifel, M., Hall, C. L., Green, H. R., Willis, A., Rennick-Egglestone, S., Juszczak, E., Townsend, M., Martin, J., & Sprange, K. (2024). Strategies to improve recruitment in mental health clinical trials: a scoping review (RE-MIND study). Trials, 25(1), Article 832. https://doi.org/10.1186/s13063-024-08665-x

Background: Lower than expected recruitment continues to be one of the major causes of trial delays, and trials to improve mental health are no exception. Indeed, recruitment challenges in trials of vulnerable populations, such as those living with m... Read More about Strategies to improve recruitment in mental health clinical trials: a scoping review (RE-MIND study).

Systematic review—understanding the barriers and facilitators experienced by healthcare professionals in providing care for tics: a mixed methods systematic review of clinical knowledge, attitudes, and practices (2024)
Journal Article
Parker, A., French, B., Groom, M. J., & Hall, C. L. (2024). Systematic review—understanding the barriers and facilitators experienced by healthcare professionals in providing care for tics: a mixed methods systematic review of clinical knowledge, attitudes, and practices. BMC Medical Education, 24, Article 1403. https://doi.org/10.1186/s12909-024-06369-z

Tic disorders (TDs) have a prevalence of approximately 1%, and while various therapies have demonstrated effectiveness, people with tics and their families report a lack of understanding by healthcare professionals (HCPs). This systematic review incl... Read More about Systematic review—understanding the barriers and facilitators experienced by healthcare professionals in providing care for tics: a mixed methods systematic review of clinical knowledge, attitudes, and practices.

Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD – are we there yet? (2024)
Journal Article
Bellato, A., Parlatini, V., Groom, M. J., Hall, C. L., Hollis, C., Simonoff, E., Thapar, A., & Cortese, S. (2025). Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD – are we there yet?. Journal of Child Psychology and Psychiatry, 66(2), 266-270. https://doi.org/10.1111/jcpp.14071

Individuals with attention-deficit/hyperactivity disorder (ADHD) exhibit varied responses to pharmacological treatments (e.g. stimulants and non-stimulants). Accurately and promptly detecting treatment-related improvements, response failure, or deter... Read More about Commentary: Using QbTest for monitoring pharmacological treatment response in ADHD – are we there yet?.

Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders (2024)
Journal Article
Hall, C. L., Le Novere, M., Murphy, T., McNally, E., Hollis, C., & Hunter, R. (2024). Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders. BMJ Mental Health, 27(1), Article e301241. https://doi.org/10.1136/bmjment-2024-301241

BACKGROUND: There are no specific national guidelines in England to guide healthcare professionals in how to assess or treat young people with tic disorders. Access to evidence-based treatment, including behavioural therapy, is of limited availabilit... Read More about Healthcare utilisation and costs associated with poor access to diagnosis and treatment for children and young people with tic disorders.

A national evaluation of QbTest to support ADHD assessment: a real-world, mixed methods approach (2024)
Journal Article
Hall, S. S., McKenzie, C., Thomson, L., Ingall, B.-R., Groom, M. J., McGlennon, N., Dines-Allen, M., & Hall, C. L. (2024). A national evaluation of QbTest to support ADHD assessment: a real-world, mixed methods approach. BMC Health Services Research, 24(1), Article 1201. https://doi.org/10.1186/s12913-024-11693-7

Background: QbTest is a commercially available, computerised test of attention, impulsivity, and activity designed to assist with the diagnosis of attention deficit hyperactivity disorder (ADHD). Health Innovation East Midlands (formerly East Midland... Read More about A national evaluation of QbTest to support ADHD assessment: a real-world, mixed methods approach.

Developing a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide (2024)
Journal Article
Taher, R., Hall, C. L., Gomez Bergin, A. D., Gupta, N., Heaysman, C., Jacobsen, P., Kabir, T., Kalnad, N., Keppens, J., Hsu, C.-W., McGuire, P., Peters, E., Shergill, S., Stahl, D., Wensley Stock, B., & Yiend, J. (2024). Developing a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide. Trials, 25, Article 604. https://doi.org/10.1186/s13063-024-08421-1

Background: The field of digital mental health has followed an exponential growth trajectory in recent years. While the evidence base has increased significantly, its adoption within health and care services has been slowed by several challenges, inc... Read More about Developing a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide.

Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges (2024)
Journal Article
Hall, C. L., Gómez Bergin, A. D., & Rennick-Egglestone, S. (2024). Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges. Journal of Medical Internet Research, 26, Article e58939. https://doi.org/10.2196/58939

Digital mental health interventions are routinely integrated into mental health services internationally, and can contribute to the reduction of the global mental health treatment gap that has been identified by the World Health Organisation. Researc... Read More about Research into digital health intervention for mental health: a 25-year retrospective on the ethical and legal challenges.

Using online methods to recruit participants into mental health clinical trials: considerations and recommendations from the RE-MIND study (2024)
Journal Article
Iflaifel, M., Hall, C. L., Green, H. R., Willis, A., Rennick-Egglestone, S., Juszczak, E., Townsend, M., Martin, J., & Sprange, K. (2024). Using online methods to recruit participants into mental health clinical trials: considerations and recommendations from the RE-MIND study. Trials, 25, Article 596. https://doi.org/10.1186/s13063-024-08435-9

Background: Ensuring diversity in clinical trials can be a challenge, which may be exacerbated when recruiting vulnerable populations, such as participants with mental health illness. As recruitment continues to be the major cause of trial delays, re... Read More about Using online methods to recruit participants into mental health clinical trials: considerations and recommendations from the RE-MIND study.

Experience of CBT in adults with ADHD: a mixed methods study (2024)
Journal Article
William, S., Horrocks, M., Richmond, J., Hall, C. L., & French, B. (2024). Experience of CBT in adults with ADHD: a mixed methods study. Frontiers in Psychiatry, 15, Article 1341624. https://doi.org/10.3389/fpsyt.2024.1341624

Introduction:
The National Institute for Health and Care Excellence (NICE) recommends Cognitive Behavioural therapy (CBT) as the psychotherapeutic treatment of choice for adults with Attention Deficit Hyperactivity Disorder (ADHD) in the UK. Howeve... Read More about Experience of CBT in adults with ADHD: a mixed methods study.

Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context (2024)
Journal Article
Taher, R., Bhanushali, P., Allan, S., Alvarez-Jimenez, M., Bolton, H., Dennison, L., Wallace, B. E., Hadjistavropoulos, H. D., Hall, C. L., Hardy, A., Henry, A. L., Lane, S., Maguire, T., Moreton, A., Moukhtarian, T. R., Perez Vallejos, E., Shergill, S., Stahl, D., Thew, G. R., Timulak, L., …Yiend, J. (2024). Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context. BJPsych Open, 10(4), Article e126. https://doi.org/10.1192/bjo.2024.713

Background
Digital Mental Health Interventions (DMHIs) that meet the definition of a medical device are regulated by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK. The MHRA uses procedures that were originally developed fo... Read More about Bridging the gap from medical to psychological safety assessment: consensus study in a digital mental health context.

The impacts associated with having ADHD: an umbrella review (2024)
Journal Article
French, B., Nalbant, G., Wright, H., Sayal, K., Daley, D., Groom, M. J., Cassidy, S., & Hall, C. L. (2024). The impacts associated with having ADHD: an umbrella review. Frontiers in Psychiatry, 15, Article 1343314. https://doi.org/10.3389/fpsyt.2024.1343314

Introduction: Attention Deficit Hyperactivity Disorder (ADHD) affects up to 5% of the population and is characterised by symptoms of impulsivity, hyperactivity and inattention. These symptoms are significantly impairing and carry additional risks for... Read More about The impacts associated with having ADHD: an umbrella review.

Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial (2024)
Journal Article
Andrén, P., Sampaio, F., Ringberg, H., Wachtmeister, V., Warnström, M., Isomura, K., Aspvall, K., Lenhard, F., Hall, C. L., Davies, E. B., Murphy, T., Hollis, C., Feldman, I., Bottai, M., Serlachius, E., Andersson, E., Fernández de la Cruz, L., & Mataix-Cols, D. (2024). Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial. JAMA Network Open, 7(5), Article e248468. https://doi.org/10.1001/jamanetworkopen.2024.8468

Importance: Behavior therapy is a recommended intervention for Tourette syndrome (TS) and chronic tic disorder (CTD), but availability is limited and long-term effects are uncertain.

Objective: To investigate the long-term efficacy and cost-effec... Read More about Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-month Follow-Up of a Randomized Clinical Trial.

Waiting-list interventions for children and young people using child and adolescent mental health services: a systematic review (2024)
Journal Article
Valentine, A. Z., Hall, S. S., Sayal, K., & Hall, C. L. (2024). Waiting-list interventions for children and young people using child and adolescent mental health services: a systematic review. BMJ Mental Health, 27(1), 1-6. https://doi.org/10.1136/bmjment-2023-300844

Question Children and young people experience delays in assessment and/or treatment within mental health services. The objective of this systematic review, funded by the Emerging Minds Network, was to explore the current evidence base for mental heal... Read More about Waiting-list interventions for children and young people using child and adolescent mental health services: a systematic review.

Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation (2023)
Journal Article
Hollis, C., Hall, C. L., Khan, K., Le Novere, M., Marston, L., Jones, R., Hunter, R., Brown, B. J., Sanderson, C., Andrén, P., Bennett, S. D., Chamberlain, L. R., Bethan Davies, E., Evans, A., Kouzoupi, N., McKenzie, C., Heyman, I., Kilgariff, J., Glazebrook, C., Mataix-Cols, D., …Murphy, T. (2023). Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation. Health Technology Assessment, 27(18), 1-120. https://doi.org/10.3310/cpms3211

Background:

Behavioural therapy for tics is difficult to access, and little is known about its effectiveness when delivered online.

Objective:

To investigate the clinical and cost-effectiveness of an online-delivered, therapist and parent-... Read More about Online Remote Behavioural Intervention for Tics in 9 to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation.

Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis (2023)
Journal Article
Bellato, A., Hall, C. L., Groom, M. J., Simonoff, E., Thapar, A., Hollis, C., & Cortese, S. (2024). Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis. Journal of Child Psychology and Psychiatry, 65(6), 845-861. https://doi.org/10.1111/jcpp.13901

Background
Several computerised cognitive tests (e.g. continuous performance test) have been developed to support the clinical assessment of attention-deficit/hyperactivity disorder (ADHD). Here, we appraised the evidence-base underpinning the use o... Read More about Practitioner Review: Clinical utility of the QbTest for the assessment and diagnosis of ADHD: a systematic review and meta-analysis.

Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial (2023)
Preprint / Working Paper
Khan, K., Hall, C. L., Babbage, C., Dodzo, S., Greenhalgh, C., Lucassen, M., Merry, S., Sayal, K., Sprange, K., Stasiak, K., Tench, C. R., Townsend, E., Stallard, P., & Hollis, C. Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial

Background:

A serious game (SPARX), developed in New Zealand and incorporating cognitive behavioural therapy (CBT) principles, has been shown to help reduce symptoms of depression and anxiety in adolescents with mild to moderate depression. Howev... Read More about Developing precision computerised cognitive behavioural therapy (cCBT) for adolescent depression: a pilot and feasibility protocol for the SPARX-UK trial.

Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study (2023)
Journal Article
Iflaifel, M., Hall, C. L., Green, H. R., Willis, A., Rennick-Egglestone, S., Juszczak, E., Townsend, M., Martin, J., & Sprange, K. (2023). Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study. BMC Medical Research Methodology, 23(1), Article 211. https://doi.org/10.1186/s12874-023-02032-1

Background:

Barriers to mental health research participation are well documented including distrust of services and research; and stigma surrounding mental health. They can contribute to a lack of diversity amongst participants in mental health r... Read More about Widening participation – recruitment methods in mental health randomised controlled trials: a qualitative study.

Remote Recruitment Strategy and Structured E-Parenting Support (STEPS) App: Feasibility and Usability Study (2023)
Journal Article
Kostyrka-Allchorne, K., Chu, P., Ballard, C., Lean, N., French, B., Hedstrom, E., Byford, S., Cortese, S., Daley, D., Downs, J., Glazebrook, C., Goldsmith, K., Hall, C. L., Kovshoff, H., Kreppner, J., Sayal, K., Shearer, J., Simonoff, E., Thompson, M., & Sonuga-Barke, E. J. (2023). Remote Recruitment Strategy and Structured E-Parenting Support (STEPS) App: Feasibility and Usability Study. JMIR Pediatrics and Parenting, 6(1), Article e47035. https://doi.org/10.2196/47035

Background: The Structured E-Parenting Support (STEPS) app [1] provides support for parents of children with elevated levels of hyperactivity/impulsivity, inattention, and conduct problems, awaiting clinical assessment by child health services. STEPS... Read More about Remote Recruitment Strategy and Structured E-Parenting Support (STEPS) App: Feasibility and Usability Study.

Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey (2023)
Journal Article
Marino, C., Khan, K., Groom, M. J., Hall, S. S., Anderson, S., Mcnally, E., Murphy, T., & Hall, C. L. (2023). Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey. BMC Health Services Research, 23, Article 788. https://doi.org/10.1186/s12913-023-09753-5

Background
Tics are common in children and young people and may persist into adulthood. Tics can cause challenges with social, occupational, physical, and academic functioning. The current study explores the perceptions of adults with tics and paren... Read More about Patients’ experience of accessing support for tics from primary care in the UK: an online mixed-methods survey.

The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know? (2023)
Journal Article
Hall, C. L., Bellato, A., Kirk, J. D., & Hollis, C. (2023). The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know?. Paediatrics and Child Health, 33(9), 259-264. https://doi.org/10.1016/j.paed.2023.06.006

The assessment of Attention-Deficit/Hyperactivity Disorder (ADHD) typically relies on subjective observer reports from parents, teachers, or the young person, combined with clinical observation and history. Children and young people often experience... Read More about The clinical utility of QbTest in supporting the assessment and monitoring of Attention-Deficit/Hyperactivity Disorder (ADHD): What do paediatricians need to know?.