All Outputs (2)

Maternal administration of anti-angiogenic agents, TNP-470 and angiostatin₄.₅, induces fetal microphthalmia (2009)
Journal Article
Rutland, C. S., Jiang, K., Soff, G. A., & Mitchell, C. A. (2009). Maternal administration of anti-angiogenic agents, TNP-470 and angiostatin₄.₅, induces fetal microphthalmia. Molecular Vision, 15, 1260-1269

Purpose: Agents specifically targeting the vasculature as a mode of therapy are finding increasing use in the clinic, primarily in the treatment of colon cancer (Avastin™) and age-related macular degeneration (Lucentis™). We have previously shown tha... Read More about Maternal administration of anti-angiogenic agents, TNP-470 and angiostatin₄.₅, induces fetal microphthalmia.

Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis (2009)
Journal Article
Rutland, C., Warner, L., Thorpe, A., Alibhai, A., Robinson, T., Shaw, B., Layfield, R., Brook, D. J., & Loughna, S. (2009). Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis. Journal of Anatomy, 214(6), 905-915. https://doi.org/10.1111/j.1469-7580.2009.01079.x

Atrial septal defects are a common congenital heart defect in humans. Although mutations in different genes are now frequently being described, little is known about the processes and mechanisms behind the early stages of atrial septal development. B... Read More about Knockdown of alpha myosin heavy chain disrupts the cytoskeleton and leads to multiple defects during chick cardiogenesis.