A proximity labelling-based approach to directly detect mRNA delivery to specific subcellular locations
(2025)
Journal Article
Smart, A. D., Hughes, M. E., Ruiz Velasco, A. D., Hori, N., Stolnik, S., & Jopling, C. L. (2025). A proximity labelling-based approach to directly detect mRNA delivery to specific subcellular locations. Molecular Therapy: Nucleic Acids, Article 102602. https://doi.org/10.1016/j.omtn.2025.102602
Messenger RNA (mRNA) therapeutics show considerable promise but face delivery challenges, as effective cytosolic entry and subsequent translation are normally limited by endosomal entrapment. While various approaches have been used to investigate det... Read More about A proximity labelling-based approach to directly detect mRNA delivery to specific subcellular locations.