All Outputs (2)

Bacteria clustering by polymers induces the expression of quorum sense controlled phenotypes (2013)
Journal Article
Lui, L. T., Xue, X., Sui, C., Brown, A., Pritchard, D. I., Halliday, N., …Alexander, C. (2013). Bacteria clustering by polymers induces the expression of quorum sense controlled phenotypes. Nature Chemistry, 5(12), https://doi.org/10.1038/nchem.1793

Bacteria deploy a range of chemistries to regulate their behaviour and respond to their environment. Quorum sensing is one mean by which bacteria use chemical reactions to modulate pre-infection behaviour such as surface attachment. Polymers that can... Read More about Bacteria clustering by polymers induces the expression of quorum sense controlled phenotypes.

Enhanced uptake of nanoparticle drug carriers via a thermoresponsive shell enhances cytotoxicity in a cancer cell line (2013)
Journal Article
Abulateefeh, S. R., Spain, S. G., Thurecht, K. J., Aylott, J. W., Chan, W. C., Garnett, M. C., & Alexander, C. (2013). Enhanced uptake of nanoparticle drug carriers via a thermoresponsive shell enhances cytotoxicity in a cancer cell line. Biomaterials Science, 1(4), 434-442. https://doi.org/10.1039/c2bm00184e

Polymer particles consisting of a biodegradable poly[lactide-co-glycolide] (PLGA) core and a thermoresponsive shell have been formulated to encapsulate the dye rhodamine 6G and the potent cytotoxic drug paclitaxel. Cellular uptake of these particles... Read More about Enhanced uptake of nanoparticle drug carriers via a thermoresponsive shell enhances cytotoxicity in a cancer cell line.