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All Outputs (2)

Reconstructing the last common ancestor of all eukaryotes (2024)
Journal Article
Richards, T. A., Eme, L., Archibald, J. M., Leonard, G., Coelho, S. M., de Mendoza, A., Dessimoz, C., Dolezal, P., Fritz-Laylin, L. K., Gabaldón, T., Hampl, V., Kops, G. J., Leger, M. M., Lopez-Garcia, P., McInerney, J. O., Moreira, D., Muñoz-Gómez, S. A., Richter, D. J., Ruiz-Trillo, I., Santoro, A. E., …Wideman, J. G. (2024). Reconstructing the last common ancestor of all eukaryotes. PLoS Biology, 22(11), Article e3002917. https://doi.org/10.1371/journal.pbio.3002917

Understanding the origin of eukaryotic cells is one of the most difficult problems in all of biology. A key challenge relevant to the question of eukaryogenesis is reconstructing the gene repertoire of the last eukaryotic common ancestor (LECA). As d... Read More about Reconstructing the last common ancestor of all eukaryotes.

A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense (2024)
Journal Article
Silvester, E., Szoor, B., Ivens, A., Awuah-Mensah, G., Gadelha, C., Wickstead, B., & Matthews, K. R. (2024). A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense. PLoS Pathogens, 20(2), Article e1011889. https://doi.org/10.1371/journal.ppat.1011889

Trypanosomatid parasites undergo developmental regulation to adapt to the different environments encountered during their life cycle. In Trypanosoma brucei, a genome wide selectional screen previously identified a regulator of the protein family ESAG... Read More about A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense.