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Enzymatic Synthesis of Functional PEGylated Adipate Copolymers (2025)
Journal Article
Axioti, E., Dixon, E. G., Jepras, T., Tin He, F., Hartman, P. J., Hopkins, B., Di Bari, V., Suksiriworapong, J., Cuzzucoli Crucitti, V., Galantini, L., Francolini, I., Cavanagh, R. J., & Taresco, V. (2025). Enzymatic Synthesis of Functional PEGylated Adipate Copolymers. ChemPlusChem, https://doi.org/10.1002/cplu.202400668

Many new active pharmaceutical ingredients (APIs) demonstrate high hydrophobicity and low water-solubility issues. In this regard, polymeric nanoparticles (NPs) have been extensively used as drug delivery carriers for the encapsulation of such APIs.... Read More about Enzymatic Synthesis of Functional PEGylated Adipate Copolymers.

Supercritical RROP: Exploring the radical ring-opening polymerisation of 2-methylene-1,3,6-trioxocane in supercritical CO2 as a green solvent (2024)
Journal Article
Mehner, F., Hopkins, B., Reynolds-Green, M., Keddie, D. J., Howdle, S. M., & Gaitzsch, J. (2024). Supercritical RROP: Exploring the radical ring-opening polymerisation of 2-methylene-1,3,6-trioxocane in supercritical CO2 as a green solvent. Polymer, 309, Article 127373. https://doi.org/10.1016/j.polymer.2024.127373

Radical ring opening polymerisation (RROP) of cyclic ketene acetals (CKAs) is an attractive technique to synthesize branched, (bio)degradable polyesters. However, CKAs as monomers of RROP suffer from hydrolysis lability, making aqueous heterogeneous... Read More about Supercritical RROP: Exploring the radical ring-opening polymerisation of 2-methylene-1,3,6-trioxocane in supercritical CO2 as a green solvent.