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All Outputs (103)

Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection (2022)
Journal Article
Crooks, C. J., West, J., Morling, J. R., Simmonds, M., Juurlink, I., Briggs, S., Cruickshank, S., Hammond-Pears, S., Shaw, D., Card, T. R., & Fogarty, A. (2022). Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection. Clinical Medicine, 22(3), 192-196. https://doi.org/10.7861/clinmed.2021-0603

Objective To determine the maximal response of the temperature and inflammatory response to SARS-CoV-2 infection and how these are modified by age.

Methods Participants were patients admitted to hospital with SARS-CoV-2 infection. For each partici... Read More about Age modifies both the maximal temperature and inflammatory response in patients with SARS-CoV-2 infection.

Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection (2022)
Journal Article
Plummer, N. R., Fogarty, A., Shaw, D., Card, T., West, J., & Crooks, C. (2022). Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection. Respiratory Medicine, 197, Article 106858. https://doi.org/10.1016/j.rmed.2022.106858

Background: We aimed to assess whether asymptomatic (“happy”) hypoxia was an identifiable physiological phenotype of COVID-19 acute respiratory distress syndrome (ARDS), and associated with need for ICU admission. Methods: We performed an observation... Read More about Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection.

Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England (2022)
Journal Article
Alothman, D., Marshall, C. R., Tyrrell, E., Lewis, S., Card, T., & Fogarty, A. (2022). Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England. Journal of Neurology, 269, 4436–4439. https://doi.org/10.1007/s00415-022-11085-z

Objective: To examine the relative risk of suicide mortality in patients with Huntington’s disease (HD). Methods: A case–control study design was used. We used linked electronic records from primary care, secondary care and Office for National Statis... Read More about Risk of mortality from suicide in patients with Huntington’s disease is increased compared to the general population in England.

Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India (2022)
Journal Article
Kulkarni, M. M., Kamath, V. G., Kamath, A., Lewis, S., Bogdanovica, I., Bains, M., Cranwell, J., Fogarty, A., Arora, M., Nazar, G. P., Ballal, K., Naik, A. K., Bhagawath, R., & Britton, J. (2022). Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India. Nicotine and Tobacco Research, 24(7), 1104-1109. https://doi.org/10.1093/ntr/ntac003

Introduction: Although most of the disease burden is due to tobacco smoking, smokeless tobacco (SLT) use contributed to an estimated 76,000 deaths in 2017. We have studied the potential risk factors for SLT use among adolescents in South India.

M... Read More about Potential Risk Factors of Smokeless Tobacco Consumption Among Adolescents in South India.

The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia (2022)
Journal Article
Tamire, M., Barker, A., Getachew, S., Murray, R. L., Amedala, R., Britton, J., Deressa, W., & Fogarty, A. W. (2022). The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia. Harm Reduction Journal, 19, Article 11. https://doi.org/10.1186/s12954-022-00591-y

Background: Excessive alcohol consumption is an important risk factor for increased morbidity, mortality and other social harms globally. Televised sport allows the promotion of alcoholic drinks to a large and often young audience, and thus can be us... Read More about The high frequency of alcohol advertising during televised English Premier League football games shown in Ethiopia.

Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis (2022)
Journal Article
Webb, K., Zain, N. M. M., Stewart, I., Fogarty, A., Nash, E. F., Whitehouse, J. L., Smyth, A. R., Lilley, A. K., Knox, A., Williams, P., Cámara, M., Bruce, K., & Barr, H. L. (2022). Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis. Journal of Medical Microbiology, 71(2), Article 001481. https://doi.org/10.1099/jmm.0.001481

Although anaerobic bacteria exist in abundance in cystic fibrosis (CF) airways, their role in disease progression is poorly understood. We hypothesized that the presence and relative abundance of the most prevalent, live, anaerobic bacteria in sputum... Read More about Porphyromonas pasteri and Prevotella nanceiensis in the sputum microbiota are associated with increased decline in lung function in individuals with cystic fibrosis.

Erratum: Chest radiograph scoring alone or combined with other risk scores for predicting outcomes in covid-19: A UK study (2021)
Journal Article
Au-Yong, I., Higashi, Y., Giannotti, E., Fogarty, A., Morling, J. R., Grainge, M., Race, A., Juurlink, I., Simmonds, M., Briggs, S., Cruickshank, S., Hammond-Pears, S., West, J., Crooks, C. J., & Card, T. (2021). Erratum: Chest radiograph scoring alone or combined with other risk scores for predicting outcomes in covid-19: A UK study. Radiology, 301(3), E444. https://doi.org/10.1148/radiol.2021219021

Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID- 19: A UK Study Iain Au-Yong, Yutaro Higashi, Elisabetta Giannotti, Andrew Fogarty, Joanne R. Morling, Matthew Grainge, Andrea Race, Irene Juurlink, Ma... Read More about Erratum: Chest radiograph scoring alone or combined with other risk scores for predicting outcomes in covid-19: A UK study.

Ethnicity and suicide risk: A population-based study from England (2021)
Journal Article
Alothman, D., Fogarty, A., Tyrrell, E., Lewis, S., & Card, T. (2022). Ethnicity and suicide risk: A population-based study from England. Journal of Affective Disorders, 298(Part A), 555-557. https://doi.org/10.1016/j.jad.2021.11.044

Using multiple linked electronic health databases, we conducted a large case-control study in England from 2001 through 2019 to examine the association between ethnicity and suicide risk. Asian, Black and Other ethnic groups had a significantly lower... Read More about Ethnicity and suicide risk: A population-based study from England.

2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis (2021)
Journal Article
Zain, N. M. M., Webb, K., Stewart, I., Halliday, N., Barrett, D. A., Nash, E. F., Whitehouse, J. L., Honeybourne, D., Smyth, A. R., Forrester, D. L., Knox, A. J., Williams, P., Fogarty, A., Cámara, M., Bruce, K. D., & Barr, H. L. (2021). 2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis. Journal of Medical Microbiology, 70(10), https://doi.org/10.1099/jmm.0.001420

Introduction. Pseudomonas aeruginosa produces quorum sensing signalling molecules including 2-alkyl-4-quinolones (AQs), which regulate virulence factor production in the cystic fibrosis (CF) airways. Hypothesis/Gap statement. Culture can lead to cond... Read More about 2-Alkyl-4-quinolone quorum sensing molecules are biomarkers for culture-independent Pseudomonas aeruginosa burden in adults with cystic fibrosis.

Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19 (2021)
Journal Article
Au-Yong, I., Higashi, Y., Giannotti, E., Fogarty, A., Morling, J. R., Grainge, M., Race, A., Juurlink, I., Simmonds, M., Briggs, S., Crooks, C. J., Cruikshank, S., Hammond-Pears, S., West, J., & Card, T. (2022). Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19. Radiology, 302(2), 460-469. https://doi.org/10.1148/radiol.2021210986

Background Radiographic severity may help predict patient deterioration and outcomes from COVID-19 pneumonia. Purpose To assess the reliability and reproducibility of three chest radiograph reporting systems (radiographic assessment of lung edema [RA... Read More about Chest Radiograph Scoring Alone or Combined with Other Risk Scores for Predicting Outcomes in COVID-19.

Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis (2021)
Journal Article
Webb, K., Cámara, M., Zain, N. M. M., Halliday, N., Bruce, K. D., Nash, E. F., Whitehouse, J. L., Knox, A., Forrester, D., Smyth, A. R., Williams, P., Fogarty, A., & Barr, H. L. (2022). Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis. Journal of Cystic Fibrosis, 21(4), 626-629. https://doi.org/10.1016/j.jcf.2021.08.030

Pseudomonas aeruginosa produces specific signalling molecules, 2-alkyl-4-quinolones (AQs) that are detectable in the sputum of adults with cystic fibrosis (CF) and who have pulmonary infection with this opportunistic pathogen. This study aimed to det... Read More about Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis.

Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India (2021)
Journal Article
Kulkarni, M. M., Kamath, A., Kamath, V. G., Lewis, S., Bogdanovica, I., Bains, M., Cranwell, J., Fogarty, A., Arora, M., Nazar, G. P., Ballal, K., Naik, A. K., Bhagawath, R., & Britton, J. (2021). Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India. PLoS ONE, 16(8), Article e0253593. https://doi.org/10.1371/journal.pone.0253593

Background Exposure to tobacco imagery in films causes young people to start smoking. Popular Indian films contain high levels of tobacco imagery, but those that do are required by law to display onscreen health warnings when smoking imagery occurs a... Read More about Prospective cohort study of exposure to tobacco imagery in popular films and smoking uptake among children in southern India.

An Emerging Problem of Shisha Smoking among High School Students in Ethiopia (2021)
Journal Article
Hirpa, S., Fogarty, A., Addissie, A., Bauld, L., Frese, T., Unverzagt, S., Kantelhardt, E. J., Getachew, S., & Deressa, W. (2021). An Emerging Problem of Shisha Smoking among High School Students in Ethiopia. International Journal of Environmental Research and Public Health, 18(13), Article 7023. https://doi.org/10.3390/ijerph18137023

Shisha smoking is also known as hookah, water pipe, goza, and nargile. Shisha use among the young is increasing globally. Shisha smoke results in a high concentration of carbon monoxide, tar, nicotine, and heavy metals which can be toxic to humans, e... Read More about An Emerging Problem of Shisha Smoking among High School Students in Ethiopia.

Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades (2021)
Journal Article
Suárez-Medina, R., Venero-Fernández, S., Mesa Ridel, G., Fogarty, A., & Lewis, S. (2021). Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades. Public Health, 191, 55-58. https://doi.org/10.1016/j.puhe.2020.11.022

Objectives

The objective of this study is to understand how Cuba responds to extreme weather events, which can help identify and disseminate good public health practice.

Study design

The study design of this study is an observational study u... Read More about Mortality rates immediately after severe hurricanes in Cuba have decreased over the past three decades.

Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety (2020)
Journal Article
Thurley, P., Bowker, R., Bhatti, I., Skelly, R., Law, R., Salaman, R., Young, B., & Fogarty, A. (2020). Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety. BMJ Open Quality, 9(4), Article e000900. https://doi.org/10.1136/bmjoq-2019-000900

Background Over recent decades, CT scans have become routinely available and are used in both acute medical and outpatient environments. However, there is a small increase in the risk of adverse consequences, including an increase in the risk of both... Read More about Development and evaluation of a brief educational cartoon on trainee clinicians’ awareness of risks of ionising-radiation exposure: a feasibility pre-post intervention study of a novel educational tool to promote patient safety.

Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study (2020)
Journal Article
Ahankari, A., Kabra, P., Tata, L., Hayter, M., & Fogarty, A. (2021). Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study. Tropical Medicine and International Health, 26(3), 327-334. https://doi.org/10.1111/tmi.13524

Objective: This study tested the hypothesis that systemic inflammation is inversely associated with haemoglobin levels in adolescent girls in India. Methods: The study population consisted of adolescent girls aged between 10 and 19years living in a r... Read More about Two measures of systemic inflammation are positively associated with haemoglobin levels in adolescent girls living in rural India: a cross-sectional study.

Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India (2020)
Journal Article
Kulkarni, M. M., Kamath, V. G., Kamath, A., Lewis, S., Bogdanovica, I., Bains, M., Cranwell, J., Fogarty, A., Arora, M., Nazar, G. P., Ballal, K., Bhagawath, R., & Britton, J. (2021). Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India. Tobacco Control, 30(5), 560-566. https://doi.org/10.1136/tobaccocontrol-2019-055353

Background Exposure to smoking in films is a recognised cause of smoking uptake among children. In India, in an attempt to protect children, films containing smoking are required to include tobacco control messaging including audiovisual disclaimers,... Read More about Exposure to tobacco imagery in popular films and the risk of ever smoking among children in southern India.

Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study (2020)
Journal Article
Young, B., Fogarty, A. W., Skelly, R., Shaw, D., Thurley, P., Sturrock, N., Norwood, M., Langley, T., Lewis, S., & Cranwell, J. (2020). Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study. Public Health, 185, 338-340. https://doi.org/10.1016/j.puhe.2020.06.023

© 2020 The Authors Objectives: There is a need to improve efficiency in healthcare delivery without compromising quality of care. One approach is the development and evaluation of behavioural strategies to reduce unnecessary use of common tests. Howe... Read More about Patients' attitudes towards cost feedback to doctors to prevent unnecessary testing: a qualitative focus group study.

Phenotypic and functional translation of IL33 genetics in asthma (2020)
Journal Article
Ketelaar, M. E., Portelli, M. A., Dijk, F. N., Shrine, N., Faiz, A., Vermeulen, C. J., Xu, C. J., Hankinson, J., Bhaker, S., Henry, A. P., Billington, C. K., Shaw, D. E., Johnson, S. R., Benest, A., Pang, V., Bates, D. O., Pogson, Z. E., Fogarty, A., McKeever, T. M., Singapuri, A., …Nawijn, M. C. (2021). Phenotypic and functional translation of IL33 genetics in asthma. Journal of Allergy and Clinical Immunology, 147(1), 144-157. https://doi.org/10.1016/j.jaci.2020.04.051

© 2020 Background: Asthma is a complex disease with multiple phenotypes that may differ in disease pathobiology and treatment response. IL33 single nucleotide polymorphisms (SNPs) have been reproducibly associated with asthma. IL33 levels are elevate... Read More about Phenotypic and functional translation of IL33 genetics in asthma.