Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells
(2015)
Journal Article
Lebert-Ghali, C.-É., Fournier, M., Kettyle, L. M., Thompson, A., Sauvageau, G., & Bijl, J. J. (2016). Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells. Blood, 127(1), 87-90. https://doi.org/10.1182/blood-2015-02-626390
Determination of defined roles for endogenous homeobox (Hox) genes in adult hematopoietic stem and progenitor cell (HSPC) activity has been hampered by a combination of embryonic defects and functional redundancy. Here we show that conditional homozy... Read More about Hoxa cluster genes determine the proliferative activity of adult mouse hematopoietic stem and progenitor cells.