All Outputs (2)

Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop (2016)
Journal Article
Borkar, A. N., Vallurupalli, P., Camilloni, C., Kay, L. E., & Vendruscolo, M. (2017). Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop. Physical Chemistry Chemical Physics, 19(4), 2797-2804. https://doi.org/10.1039/c6cp08313g

© the Owner Societies 2017. RNA molecules in solution tend to undergo structural fluctuations of relatively large amplitude and to populate a range of different conformations some of which with low populations. It is still very challenging, however,... Read More about Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop.

Structure of a low-population binding intermediate in protein-RNA recognition (2016)
Journal Article
Borkar, A. N., Bardaro, M. F., Camilloni, C., Aprile, F. A., Varani, G., & Vendruscolo, M. (2016). Structure of a low-population binding intermediate in protein-RNA recognition. Proceedings of the National Academy of Sciences, 113(26), 7171-7176. https://doi.org/10.1073/pnas.1521349113

All biochemical reactions in living organisms require molecular recognition events. In particular, the interactions between protein and RNA molecules are crucial in the regulation of gene expression. However, the transient nature of the conformations... Read More about Structure of a low-population binding intermediate in protein-RNA recognition.