Examining the relationship between fatigue and cognition after stroke: a systematic review

Lagogianni, Christodouli; Thomas, Shirley A.; Lincoln, Nadina

Abstract

Many stroke survivors experience fatigue, which is associated with a variety of factors including cognitive impairment. A few studies have examined the relationship between fatigue and cognition and have obtained conflicting results. The aim of the current study was to review the literature on the relationship between fatigue and cognition post-stroke. The following databases were searched: EMBASE (1980–February, 2014), PsycInfo (1806–February, 2014), CINAHL (1937–February, 2014), MEDLINE (1946–February, 2014), Ethos (1600–February, 2014) and DART (1999–February, 2014). Reference lists of relevant papers were screened and the citation indices of the included papers were searched using Web of Science. Studies were considered if they were on adult stroke patients and assessed the following: fatigue with quantitative measurements (≥ 3 response categories), cognition using objective measurements, and the relationship between fatigue and cognition. Overall, 413 papers were identified, of which 11 were included. Four studies found significant correlations between fatigue and memory, attention, speed of information processing and reading speed (r = −.36 to .46) whereas seven studies did not. Most studies had limitations; quality scores ranged from 9 to 14 on the Critical Appraisal Skills Programme Checklists. There was insufficient evidence to support or refute a relationship between fatigue and cognition post-stroke. More robust studies are needed.

Citation

Lagogianni, C., Thomas, S. A., & Lincoln, N. (2018). Examining the relationship between fatigue and cognition after stroke: a systematic review. Neuropsychological Rehabilitation, 28(1), 57-116. https://doi.org/10.1080/09602011.2015.1127820

• Journal Article Type: Article
• Acceptance Date: Nov 30, 2015
• Online Publication Date: Jan 1, 2016
• Publication Date: 2018
• Deposit Date: Mar 20, 2017
• Publicly Available Date: Mar 20, 2017
• Journal: Neuropsychological Rehabilitation
• Print ISSN: 0960-2011
• Electronic ISSN: 1464-0694
• Publisher: Routledge
• Peer Reviewed: Peer Reviewed
• Volume: 28
• Issue: 1
• Pages: 57-116
• DOI: https://doi.org/10.1080/09602011.2015.1127820
• Keywords: Stroke, fatigue, cognition, systematic review
• Public URL: https://nottingham-repository.worktribe.com/output/980140
• Publisher URL: http://www.tandfonline.com/doi/full/10.1080/09602011.2015.1127820
• Additional Information: This is an Accepted Manuscript of an article published by Taylor & Francis in Neuropsychological Rehabilitation on 20.01.2017, available online: http://www.tandfonline.com/10.1080/09602011.2015.1127820
• Contract Date: Mar 20, 2017