Handgrip strength cannot be assumed a proxy for overall muscle strength

Yeung, Suey S.Y.; Reijnierse, Esmee M.; Trappenburg, Marijke C.; Hogrel, Jean-Yves; McPhee, Jamie S.; Piasecki, Mathew; Sipila, Sarianna; Salpakoski, Anu; Butler-Browne, Gillian; P��suke, Mati; Gapeyeva, Helena; Narici, Marco V.; Meskers, Carel G.M.; Maier, Andrea B.

Abstract

Objectives: Dynapenia, low muscle strength, is predictive for negative health outcomes and is usually expressed as handgrip strength (HGS). Whether HGS can be a proxy for overall muscle strength and whether this depends on age and health status is controversial. This study assessed the agreement between HGS and knee extension strength (KES) in populations differing in age and health status.
Design: Data were retrieved from 5 cohorts.
Setting and Participants: Community, geriatric outpatient clinics, and a hospital. Five cohorts (960 individuals, 49.8% male) encompassing healthy young and older individuals, geriatric outpatients, and older individuals post hip fracture were included.
Measures: HGS and KES were measured according to the protocol of each cohort. Pearson correlation was performed to analyze the association between HGS and KES, stratified by sex. HGS and KES were standardized into sex-specific z scores. The agreement between standardized HGS and standardized KES at population level and individual level were assessed by intraclass correlation coefficients (ICC) and Bland-Altman analysis.
Results: Pearson correlation coefficients were low in healthy young (male: 0.36 to 0.45, female: 0.45) and healthy older individuals (male: 0.35 to 0.37, female: 0.44), and moderate in geriatric outpatients (male and female: 0.54) and older individuals post hip fracture (male: 0.44, female: 0.57) (P<.05, except for male older individuals post hip fracture [P¼.07]). Intraclass correlation coefficient values were poor to moderate in all populations (ie, healthy young individuals [0.41, 0.45], healthy older individuals [0.37, 0.41, 0.44], geriatric outpatients [0.54], and older individuals post hip fracture [0.54]). Bland-Altman analysis showed that within the same population of age and health status, agreement between HGS and KES varied on individual level.

Citation

Yeung, S. S., Reijnierse, E. M., Trappenburg, M. C., Hogrel, J.-Y., McPhee, J. S., Piasecki, M., Sipila, S., Salpakoski, A., Butler-Browne, G., Pääsuke, M., Gapeyeva, H., Narici, M. V., Meskers, C. G., & Maier, A. B. (2018). Handgrip strength cannot be assumed a proxy for overall muscle strength. Journal of the American Medical Directors Association, 19(8), 703-709. https://doi.org/10.1016/j.jamda.2018.04.019

• Journal Article Type: Article
• Acceptance Date: Apr 29, 2018
• Online Publication Date: Jun 20, 2018
• Publication Date: 2018-08
• Deposit Date: Jun 21, 2018
• Publicly Available Date: Jun 21, 2019
• Journal: Journal of the American Medical Directors Association
• Print ISSN: 1525-8610
• Electronic ISSN: 1538-9375
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 19
• Issue: 8
• Pages: 703-709
• DOI: https://doi.org/10.1016/j.jamda.2018.04.019
• Keywords: Muscle strength; knee extension strength; aged; geriatric assessment
• Public URL: https://nottingham-repository.worktribe.com/output/940233
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S1525861018302366
• Additional Information: This article is maintained by: Elsevier; Article Title: Handgrip Strength Cannot Be Assumed a Proxy for Overall Muscle Strength; Journal Title: Journal of the American Medical Directors Association; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.jamda.2018.04.019; Content Type: article; Copyright: © 2018 AMDA - The Society for Post-Acute and Long-Term Care Medicine.
• Contract Date: Jun 21, 2018