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Interventions for preventing occupational irritant hand dermatitis (Review)


Andrea Bauer


Peter Elsner

Daan Dittmar

Cathy Bennett

Marie-Louise Anna Schuttelaar


Swen Malthe John

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Professor of Dermato-Epidemiology


Occupational irritant hand dermatitis (OIHD) causes significant functional impairment, disruption of work, and discomfort in the working population. Different preventive measures such as protective gloves, barrier creams and moisturisers can be used, but it is not clear how effective these are. This is an update of a Cochrane review which was previously published in 2010.
To assess the effects of primary preventive interventions and strategies (physical and behavioural) for preventing OIHD in healthy people (who have no hand dermatitis) who work in occupations where the skin is at risk of damage due to contact with water, detergents, chemicals or other irritants, or from wearing gloves.
Search methods:
We updated our searches of the following databases to January 2018: the Cochrane Skin Specialised Register, CENTRAL, MEDLlNE, and Embase. We also searched five trials registers and checked the bibliographies of included studies for further references to relevant trials. We handsearched two sets of conference proceedings.
Selection criteria:
We included parallel and cross-over randomised controlled trials (RCTs) which examined the effectiveness of barrier creams, moisturisers, gloves, or educational interventions compared to no intervention for the primary prevention of OIHD under field conditions.
Data collection and analysis:
We used the standard methodological procedures expected by Cochrane. The primary outcomes were signs and symptoms of OIHD developed during the trials, and the frequency of treatment discontinuation due to adverse effects.


Bauer, A., Rönsch, H., Elsner, P., Dittmar, D., Bennett, C., Schuttelaar, M. A., …Williams, H. C. (in press). Interventions for preventing occupational irritant hand dermatitis (Review). Cochrane Database of Systematic Reviews,

Journal Article Type Article
Acceptance Date Apr 5, 2018
Online Publication Date Apr 30, 2018
Deposit Date May 22, 2018
Publicly Available Date May 1, 2019
Journal Cochrane Database of Systematic Reviews
Electronic ISSN 1469-493X
Publisher Cochrane Collaboration
Peer Reviewed Peer Reviewed
Public URL
Publisher URL


CD004414.pdf (1.1 Mb)

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