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Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis

Herrod, Philip J.J.; Doleman, Brett; Blackwell, James E.M.; O�Boyle, Francesca; Williams, John P.; Lund, Jonathan N.; Phillips, Bethan E.

Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis Thumbnail


Authors

Philip J.J. Herrod

Brett Doleman

James E.M. Blackwell

Francesca O�Boyle

JOHN WILLIAMS john.williams7@nottingham.ac.uk
Clinical Associate Professor

JONATHAN LUND JON.LUND@NOTTINGHAM.AC.UK
Clinical Associate Professor

BETH PHILLIPS beth.phillips@nottingham.ac.uk
Professor of Translational Physiology



Abstract

The incidence of hypertension increases with advancing age and represents a significant burden of disease. Lifestyle modification represents the first-line intervention in treatment algorithms; however, the majority of evidence for this comes from studies involving young participants using interventions that may not always be feasible in the elderly. This manuscript presents a systematic review of all randomized controlled trials involving participants with a mean age of 65 or over investigating nonpharmacological strategies to reduce blood pressure (BP). Fifty-three randomized controlled trials were included. The majority of interventions described aerobic exercise training, dynamic resistance exercise training, or combined aerobic and dynamic resistance exercise training (COM), with limited studies reporting isometric exercise training or alternative lifestyle strategies. Aerobic exercise training, dynamic resistance exercise training, COM, and isometric exercise training all elicited significant reductions in both systolic and diastolic BP, with no additional benefit of COM compared with single modality exercise training. Three months of traditional exercise-based lifestyle intervention may produce a reduction in BP of approximately 5 mmHg systolic and 3 mmHg diastolic in older individuals, similar to that expected in younger individuals.

Citation

Herrod, P. J., Doleman, B., Blackwell, J. E., O’Boyle, F., Williams, J. P., Lund, J. N., & Phillips, B. E. (in press). Exercise and other nonpharmacological strategies to reduce blood pressure in older adults: a systematic review and meta-analysis. Journal of the American Society of Hypertension, 12(4), https://doi.org/10.1016/j.jash.2018.01.008

Journal Article Type Article
Acceptance Date Jan 18, 2018
Online Publication Date Feb 2, 2018
Deposit Date May 15, 2018
Publicly Available Date Feb 3, 2019
Journal Journal of the American Society of Hypertension
Print ISSN 1933-1711
Electronic ISSN 1878-7436
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 12
Issue 4
DOI https://doi.org/10.1016/j.jash.2018.01.008
Keywords Elderly; hypertension; non-drug
Public URL https://nottingham-repository.worktribe.com/output/908507
Publisher URL https://www.sciencedirect.com/science/article/pii/S1933171118300093?via%3Dihub

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