Dr JOANNE STOCKS JOANNE.STOCKS@NOTTINGHAM.AC.UK
Senior Research Fellow
Bidirectional association between disturbed sleep and neuropathic pain symptoms: a prospective cohort study in post-total joint replacement participants
Stocks, Joanne; Tang, Nicole K.Y.; Walsh, David A.; Warner, Sophie C.; Harvey, Hollie; Jenkins, Wendy; Abhishek, Abhishek; Doherty, Michael; Valdes, Ana M.
Authors
Nicole K.Y. Tang
DAVID WALSH david.walsh@nottingham.ac.uk
Professor of Rheumatology
Sophie C. Warner
Hollie Harvey
Wendy Jenkins
ABHISHEK ABHISHEK ABHISHEK.ABHISHEK@NOTTINGHAM.AC.UK
Clinical Professor
Michael Doherty
Professor ANA VALDES Ana.Valdes@nottingham.ac.uk
Professor of Molecular & Genetic Epidemiology
Abstract
Disturbed sleep is strongly correlated with chronic pain. The aim of this study was to examine the association between sleep disturbance and incident joint pain focusing on neuropathic pain-like symptoms. 423 individuals who had undergone total joint replacement (TJR) for osteoarthritis (OA) were assessed 3.6 years post-surgery, using the Medical Outcomes Survey sleep subscale, the WOMAC and PainDETECT instruments, and again 5.9 years post-TJR. Cox hazards ratios (HR) and 95% confidence intervals (CIs) were computed adjusting for age, BMI, sex, use of hypnotic and analgesic medication. The presence of neuropathic pain symptoms predicted incidence of disturbed sleep after adjustment for covariates and pain severity (aHR 2.01, 95% CI: 1.00-4.10 p
Citation
Stocks, J., Tang, N. K., Walsh, D. A., Warner, S. C., Harvey, H., Jenkins, W., …Valdes, A. M. (2018). Bidirectional association between disturbed sleep and neuropathic pain symptoms: a prospective cohort study in post-total joint replacement participants. Journal of Pain Research, 2018(11), 1087—1093. https://doi.org/10.2147/JPR.S149830
Journal Article Type | Article |
---|---|
Acceptance Date | Nov 29, 2017 |
Publication Date | Jun 6, 2018 |
Deposit Date | Dec 5, 2017 |
Publicly Available Date | Aug 16, 2018 |
Journal | Journal of Pain Research |
Electronic ISSN | 1178-7090 |
Publisher | Dove Medical Press |
Peer Reviewed | Peer Reviewed |
Volume | 2018 |
Issue | 11 |
Pages | 1087—1093 |
DOI | https://doi.org/10.2147/JPR.S149830 |
Keywords | total joint replacement; opioids; osteoarthritis; |
Public URL | https://nottingham-repository.worktribe.com/output/896896 |
Publisher URL | https://www.dovepress.com/bidirectional-association-between-disturbed-sleep-and-neuropathic-pain-peer-reviewed-article-JPR |
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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf
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