Single addition of an allyl amine monomer enables access to end-functionalized RAFT polymers via native chemical ligation

Isahak, Naatasha; Gody, Guillaume; Malins, Lara R.; Mitchell, Nicholas J.; Payne, Richard J.; Perrier, Sebastien

Abstract

A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalisation of polymers with peptides.

Citation

Isahak, N., Gody, G., Malins, L. R., Mitchell, N. J., Payne, R. J., & Perrier, S. (in press). Single addition of an allyl amine monomer enables access to end-functionalized RAFT polymers via native chemical ligation. Chemical Communications, 52, https://doi.org/10.1039/C6CC06010B

• Journal Article Type: Article
• Acceptance Date: Sep 21, 2016
• Online Publication Date: Sep 23, 2016
• Deposit Date: Dec 12, 2016
• Publicly Available Date: Dec 12, 2016
• Journal: Chemical Communications
• Print ISSN: 1359-7345
• Electronic ISSN: 1364-548X
• Publisher: Royal Society of Chemistry
• Peer Reviewed: Peer Reviewed
• Volume: 52
• DOI: https://doi.org/10.1039/C6CC06010B
• Public URL: https://nottingham-repository.worktribe.com/output/809630
• Publisher URL: http://pubs.rsc.org/en/Content/ArticleLanding/2016/CC/C6CC06010B#!divAbstract
• Contract Date: Dec 12, 2016