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Moving rehabilitation research forward: developing consensus statements for rehabilitation and recovery research

Bernhardt, Julie; Borschmann, Karen; Boyd, Lara; Thomas Carmichael, S.; Corbett, Dale; Cramer, Steven C.; Hoffmann, Tammy C.; Kwakkel, Gert; Savitz, Sean I.; Saposnik, Gustavo; Walker, Marion; Ward, Nick

Authors

Julie Bernhardt

Karen Borschmann

Lara Boyd

S. Thomas Carmichael

Dale Corbett

Steven C. Cramer

Tammy C. Hoffmann

Gert Kwakkel

Sean I. Savitz

Gustavo Saposnik

Marion Walker

Nick Ward



Abstract

Stroke recovery is the next frontier in stroke medicine. While growth in rehabilitation and recovery research is exponential, a number of barriers hamper our ability to rapidly progress the field. Standardized terminology is absent in both animal and human research, methods are poorly described, recovery biomarkers are not well defined, and we lack consistent timeframes or measures to examine outcomes. Agreed methods and conventions for developing, monitoring, evaluating and reporting interventions directed at improving recovery are lacking, and current approaches are often not underpinned by biology. We urgently need to better understand the biology of recovery and its time course in both animals and humans to translate evidence from basic science into clinical trials. A new international partnership of stroke recovery and rehabilitation experts has committed to advancing the research agenda. In May 2016, the first Stroke Recovery and Rehabilitation Roundtable will be held, with the aim of achieving an agreed approach to the development, conduct and reporting of research. A range of methods will be used to achieve consensus in four priority areas: preclinical recovery research; biomarkers of recovery; intervention development, monitoring and reporting; and measurement in clinical trials. We hope to foster a global network of researchers committed to advancing this exciting field. Recovery from stroke is challenging for many survivors. They deserve effective treatments underpinned by our evolving understanding of brain recovery and human behaviour. Working together, we can develop game-changing interventions to improve recovery and quality of life in those living with stroke.

Citation

Bernhardt, J., Borschmann, K., Boyd, L., Thomas Carmichael, S., Corbett, D., Cramer, S. C., …Ward, N. (in press). Moving rehabilitation research forward: developing consensus statements for rehabilitation and recovery research. International Journal of Stroke, 11(4), https://doi.org/10.1177/1747493016643851

Journal Article Type Article
Acceptance Date Mar 15, 2016
Online Publication Date Apr 12, 2016
Deposit Date Nov 1, 2016
Publicly Available Date Nov 1, 2016
Journal International Journal of Stroke
Print ISSN 1747-4930
Electronic ISSN 1747-4949
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 11
Issue 4
DOI https://doi.org/10.1177/1747493016643851
Keywords Consensus, neurobiology, recovery, rehabilitation, recommendations, stroke
Public URL http://eprints.nottingham.ac.uk/id/eprint/38395
Publisher URL http://wso.sagepub.com/content/11/4/454
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf

Files


111 Consensus Statement Bernhardt et al IJS 2016 accepted 15Mar16.pdf (167 Kb)
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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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