Highlights of children with Cancer UK’s workshop on drug delivery in paediatric brain tumours

Nailor, Audrey; Walker, David A.; Jacques, Thomas S.; Warren, Kathy E.; Brem, Henry; Kearns, Pamela R.; Greenwood, John; Penny, Jeffrey I.; Pilkington, Geoffrey J.; Carcaboso, Angel M.; Fleischhack, Gudrun; Macarthur, Donald; Slavc, Irene; Meijer, Lisethe; Gill, Steven; Lowis, Stephen; van Vuurden, Dannis G.; Pearl, Monica S.; Clifford, Steven C.; Morrissy, A. Sorana; Ivanov, Delyan P.; Beccaria, K�vin; Gilbertson, Richard J.; Straathof, Karin; Green, Jordan J.; Smith, Stuart; Rahman, Ruman; Kilday, John-Paul

Abstract

The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challenges presented by the blood–brain barrier, the underpinning reasons for the intractability of CNS cancers, and the practical difficulties of delivering cancer treatment to the brains of children. Novel techniques for overcoming these problems were discussed, new models brought forth, and experiences compared.

Citation

Nailor, A., Walker, D. A., Jacques, T. S., Warren, K. E., Brem, H., Kearns, P. R., Greenwood, J., Penny, J. I., Pilkington, G. J., Carcaboso, A. M., Fleischhack, G., Macarthur, D., Slavc, I., Meijer, L., Gill, S., Lowis, S., van Vuurden, D. G., Pearl, M. S., Clifford, S. C., Morrissy, A. S., …Kilday, J.-P. (2016). Highlights of children with Cancer UK’s workshop on drug delivery in paediatric brain tumours. ecancermedicalscience, 10(630), https://doi.org/10.3332/ecancer.2016.630

• Journal Article Type: Article
• Acceptance Date: Jan 11, 2016
• Publication Date: Mar 31, 2016
• Deposit Date: Oct 18, 2016
• Publicly Available Date: Oct 18, 2016
• Journal: ecancermedicalscience
• Electronic ISSN: 1754-6605
• Publisher: Cancer Intelligence
• Peer Reviewed: Peer Reviewed
• Volume: 10
• Issue: 630
• DOI: https://doi.org/10.3332/ecancer.2016.630
• Keywords: Drug delivery, translational medicine, paediatrics, brain tumours, glioma, medulloblastoma, CNS involvement, blood-brain barrier
• Public URL: https://nottingham-repository.worktribe.com/output/778446
• Publisher URL: http://ecancer.org/journal/10/full/630-highlights-of-children-with-cancer-uk-s-workshop-on-drug-delivery-in-paediatric-brain-tumours.php
• Contract Date: Oct 18, 2016