An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging

Andersson, Jesper L.R.; Sotiropoulos, Stamatios N.

Abstract

In this paper we describe a method for retrospective estimation and correction of eddy current (EC)-induced distortions and subject movement in diffusion imaging. In addition a susceptibility-induced field can be supplied and will be incorporated into the calculations in a way that accurately reflects that the two fields (susceptibility- and EC-induced) behave differently in the presence of subject movement. The method is based on registering the individual volumes to a model free prediction of what each volume should look like, thereby enabling its use on high b-value data where the contrast is vastly different in different volumes. In addition we show that the linear EC-model commonly used is insufficient for the data used in the present paper (high spatial and angular resolution data acquired with Stejskal–Tanner gradients on a 3 T Siemens Verio, a 3 T Siemens Connectome Skyra or a 7 T Siemens Magnetome scanner) and that a higher order model performs significantly better.

The method is already in extensive practical use and is used by four major projects (the WU-UMinn HCP, the MGH HCP, the UK Biobank and the Whitehall studies) to correct for distortions and subject movement.

Citation

Andersson, J. L., & Sotiropoulos, S. N. (2016). An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging. NeuroImage, 125, https://doi.org/10.1016/j.neuroimage.2015.10.019

• Journal Article Type: Article
• Acceptance Date: Oct 9, 2015
• Online Publication Date: Oct 20, 2015
• Publication Date: Jan 15, 2016
• Deposit Date: Apr 5, 2018
• Publicly Available Date: Apr 5, 2018
• Journal: NeuroImage
• Print ISSN: 1053-8119
• Electronic ISSN: 1053-8119
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 125
• DOI: https://doi.org/10.1016/j.neuroimage.2015.10.019
• Keywords: Diffusion; Eddy current; Movement; Susceptibility; Registration
• Public URL: http://eprints.nottingham.ac.uk/id/eprint/50939
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S1053811915009209
• Copyright Statement: Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0