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Multi-exposure laser speckle contrast imaging using a high frame rate CMOS sensor with a field programmable gate array

Sun, Shen; Hayes-Gill, Barrie R.; He, Diwei; Zhu, Yiqun; Morgan, Stephen P.

Authors

Shen Sun

BARRIE HAYES-GILL BARRIE.HAYES-GILL@NOTTINGHAM.AC.UK
Professor of Electronic Systems and Medical Devices

Diwei He

YIQUN ZHU YIQUN.ZHU@NOTTINGHAM.AC.UK
Assistant Professor



Abstract

A system has been developed in which multi-exposure Laser Speckle Contrast Imaging (LSCI) is implemented using a high frame rate CMOS imaging sensor chip. Processing is performed using a Field Programmable Gate Array (FPGA). The system allows different exposure times to be simulated by accumulating a number of short exposures. This has the advantage that the image acquisition time is limited by the maximum exposure time and that regulation of the illuminating light level is not required. This high frame rate camera has also been deployed to implement laser Doppler blood flow processing enabling direct comparison of multi-exposure laser speckle contrast imaging and Laser Doppler Imaging (LDI) to be carried out using the same experimental data. Results from a rotating diffuser indicate that both multi-exposure LSCI and LDI provide a linear response to changes in velocity. This cannot be obtained using single-exposure LSCI unless an appropriate model is used for correcting the response.

Journal Article Type Article
Publication Date Oct 5, 2015
Journal Optics Letters
Print ISSN 0146-9592
Electronic ISSN 0146-9592
Publisher Optical Society of America
Peer Reviewed Peer Reviewed
Volume 40
Issue 20
APA6 Citation Sun, S., Hayes-Gill, B. R., He, D., Zhu, Y., & Morgan, S. P. (2015). Multi-exposure laser speckle contrast imaging using a high frame rate CMOS sensor with a field programmable gate array. Optics Letters, 40(20), https://doi.org/10.1364/OL.40.004587
DOI https://doi.org/10.1364/OL.40.004587
Publisher URL https://www.osapublishing.org/ol/abstract.cfm?uri=ol-40-20-4587
Copyright Statement Copyright information regarding this work can be found at the following address: http://eprints.nottingh.../end_user_agreement.pdf
Additional Information © 2015 Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modifications of the content of this paper are prohibited.

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Multi-Exposure Laser Speckle Contrast Imaging using a High Frame Rate CMOS Sensor with a Field Programmable Gate Array Revision ID245669.pdf (480 Kb)
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Copyright Statement
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf





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