Furqaan Ahmed Kaji
Rare central nervous system lymphomas
Authors
Martinez?Calle
Vishakha Sovani
CHRIS FOX Christopher.Fox@nottingham.ac.uk
Clinical Professor in Haematology
Abstract
Central nervous system (CNS) lymphomas are rare malignancies characterised by lymphoid infiltration into the brain, spinal cord, cranial nerves, meninges and/or eyes in the presence or absence of previous or concurrent systemic disease. Most CNS lymphomas are of the diffuse large B-cell lymphoma (DLBCL) subtype for which treatment strategies, particularly the use of high-dose methotrexate-based protocols and consolidation with autologous stem cell transplantation, are well established. Other histopathological subtypes of CNS lymphoma are comparatively less common with published data on these rare lymphomas dominated by smaller case series and retrospective reports. Consequently, there exists little clinical consensus on the optimal methods to diagnose and manage these clinically and biologically heterogeneous CNS lymphomas. In this review article, we focus on rarer CNS lymphomas, summarising the available clinical data on incidence, context, diagnostic features, reported management strategies, and clinical outcomes.
Citation
Kaji, F. A., Martinez?Calle, N., Sovani, V., & Fox, C. P. (2022). Rare central nervous system lymphomas. British Journal of Haematology, 197(6), 662-678. https://doi.org/10.1111/bjh.18128
Journal Article Type | Review |
---|---|
Acceptance Date | Feb 23, 2022 |
Online Publication Date | Mar 16, 2022 |
Publication Date | 2022-06 |
Deposit Date | Mar 22, 2022 |
Publicly Available Date | Mar 22, 2022 |
Journal | British Journal of Haematology |
Print ISSN | 0007-1048 |
Electronic ISSN | 1365-2141 |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
Volume | 197 |
Issue | 6 |
Pages | 662-678 |
DOI | https://doi.org/10.1111/bjh.18128 |
Keywords | Hematology |
Public URL | https://nottingham-repository.worktribe.com/output/7643674 |
Publisher URL | https://onlinelibrary.wiley.com/doi/10.1111/bjh.18128 |
Files
Rare central nervous system lymphomas
(<nobr>2.6 Mb</nobr>)
PDF
Publisher Licence URL
http://creativecommons.org/licenses/by/4.0/
You might also like
A realist evaluation of a multifactorial falls prevention programme in care homes
(2022)
Journal Article
Management of secondary central nervous system lymphoma
(2022)
Journal Article
Extranodal natural killer/T-cell lymphoma: An overview on pathology and clinical management
(2022)
Journal Article