Electrochemical Oscillatory Baffled Reactors Fabricated with Additive Manufacturing for Efficient Continuous-Flow Oxidations

Alvarez, Elena; Romero-Fernandez, Maria; Iglesias, Diego; Martinez-Cuenca, Raul; Okafor, Obinna; Delorme, Astrid; Lozano, Pedro; Goodridge, Ruth; Paradisi, Francesca; Walsh, Darren A.; Sans, Victor

Abstract

Electrochemical continuous-flow reactors offer a great opportunity for enhanced and sustainable chemical syntheses. Here, we present a novel application of electrochemical continuous-flow oscillatory baffled reactors (ECOBRs) that combines advanced mixing features with electrochemical transformations to enable efficient electrochemical oxidations under continuous flow at a millimeter distance between electrodes. Different additive manufacturing techniques have been employed to rapidly fabricate reactors. The electrochemical oxidation of NADH, a very sensitive substrate key for the regeneration of enzymes in biocatalytic transformations, has been employed as a benchmark reaction. The oscillatory conditions improved bulk mixing, facilitating the contact of reagents to electrodes. Under oscillatory conditions, the ECOBR demonstrated improved performance in the electrochemical oxidation of NADH, which is attributed to improved mass transfer associated with the oscillatory regime.

Citation

Alvarez, E., Romero-Fernandez, M., Iglesias, D., Martinez-Cuenca, R., Okafor, O., Delorme, A., Lozano, P., Goodridge, R., Paradisi, F., Walsh, D. A., & Sans, V. (2022). Electrochemical Oscillatory Baffled Reactors Fabricated with Additive Manufacturing for Efficient Continuous-Flow Oxidations. ACS Sustainable Chemistry and Engineering, 10(7), 2388-2396. https://doi.org/10.1021/acssuschemeng.1c06799

• Journal Article Type: Article
• Acceptance Date: Jan 14, 2022
• Online Publication Date: Feb 11, 2022
• Publication Date: Feb 21, 2022
• Deposit Date: Feb 18, 2022
• Publicly Available Date: Feb 18, 2022
• Journal: ACS Sustainable Chemistry & Engineering
• Electronic ISSN: 2168-0485
• Publisher: American Chemical Society
• Peer Reviewed: Peer Reviewed
• Volume: 10
• Issue: 7
• Pages: 2388-2396
• DOI: https://doi.org/10.1021/acssuschemeng.1c06799
• Keywords: Renewable Energy, Sustainability and the Environment; General Chemical Engineering; Environmental Chemistry; General Chemistry
• Public URL: https://nottingham-repository.worktribe.com/output/7417305
• Publisher URL: https://pubs.acs.org/doi/10.1021/acssuschemeng.1c06799