Does clopidogrel or clopidogrel plus aspirin result in longer survival times in cats with hypertrophic cardiomyopathy?

O'Reilly, Hayley; Brennan, Marnie

Abstract

An apparently healthy cat has a heart murmur detected at vaccination yet no other abnormalities are found on clinical exam. The owner opts for further investigation and hypertrophic cardiomyopathy is confirmed after performing ultrasound of the heart. The owner has read up on the condition and is worried about the risk of clot formation as these cats have a higher risk of arterial thromboembolism. You have seen clopidogrel used frequently as an antithrombotic agent but have heard some specialists advise the use of both clopidogrel and aspirin together for cats with hypertrophic cardiomyopathy. You wonder if there is any benefit to using both instead of just clopidogrel for increasing longevity... 3-Part Question (PICO) In [cats with hypertrophic cardiomyopathy] does [clopidogrel versus clopidogrel plus aspirin] [increase survival time]?

Citation

O'Reilly, H., & Brennan, M. (2021). Does clopidogrel or clopidogrel plus aspirin result in longer survival times in cats with hypertrophic cardiomyopathy?. Veterinary Record, 189(10), 404-404. https://doi.org/10.1002/vetr.1198

• Journal Article Type: Article
• Acceptance Date: Nov 19, 2021
• Online Publication Date: Nov 19, 2021
• Publication Date: Nov 20, 2021
• Deposit Date: Dec 22, 2021
• Publicly Available Date: Nov 20, 2022
• Journal: Veterinary Record
• Print ISSN: 0042-4900
• Electronic ISSN: 2042-7670
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 189
• Issue: 10
• Pages: 404-404
• DOI: https://doi.org/10.1002/vetr.1198
• Keywords: General Veterinary; General Medicine
• Public URL: https://nottingham-repository.worktribe.com/output/7056729
• Publisher URL: https://bvajournals.onlinelibrary.wiley.com/doi/epdf/10.1002/vetr.1198
• Additional Information: This is the peer reviewed version of the following article: O'Reilly, H. and Brennan, M. (2021), Does clopidogrel or clopidogrel plus aspirin result in longer survival times in cats with hypertrophic cardiomyopathy?. Veterinary Record, 189: 404-404, which has been published in final form at https://doi.org/10.1002/vetr.1198. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.