Nitro to amine reductions using aqueous flow catalysis under ambient conditions

Yaghmaei, Mahzad; Lanterna, Anabel E.; Scaiano, Juan C.

Abstract

A catalyst based on Pd on glass wool (Pd@GW) shows exceptional performance and durability for the reduction of nitrobenzene to aniline at room temperature and ambient pressure in aqueous solutions. The reaction is performed in a flow system and completed with 100% conversion under a variety of flow rates, 2 to 100 mLmin−1 (normal laboratory fast flow conditions). Sodium borohydride or dihydrogen perform well as reducing agents. Scale-up of the reaction to flows of 100 mLmin−1 also shows high conversions and robust catalytic performance. Catalyst deactivation can be readily corrected by flowing a NaBH4 solution. The catalytic system proves to be generally efficient, performing well with a range of nitroaromatic compounds. The shelf life of the catalyst is excellent and its reusability after 6-8 months of storage showed the same performance as for the fresh catalyst.

Citation

Yaghmaei, M., Lanterna, A. E., & Scaiano, J. C. (2021). Nitro to amine reductions using aqueous flow catalysis under ambient conditions. iScience, 24(12), Article 103472. https://doi.org/10.1016/j.isci.2021.103472

• Journal Article Type: Article
• Acceptance Date: Nov 17, 2021
• Online Publication Date: Nov 18, 2021
• Publication Date: Dec 17, 2021
• Deposit Date: Nov 18, 2021
• Publicly Available Date: Jan 20, 2022
• Journal: iScience
• Electronic ISSN: 2589-0042
• Publisher: Cell Press
• Peer Reviewed: Peer Reviewed
• Volume: 24
• Issue: 12
• Article Number: 103472
• DOI: https://doi.org/10.1016/j.isci.2021.103472
• Keywords: Chemistry; Catalysis; Green chemistry; Engineering
• Public URL: https://nottingham-repository.worktribe.com/output/6737379
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S2589004221014437?via%3Dihub