Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial

Fleminger, Jessica; Duhig, Kate; Seed, Paul T.; Brocklehurst, Peter; Green, Marcus; Juszczak, Edmund; Marlow, Neil; Shennan, Andrew; Chappell, Lucy

Abstract

This secondary analysis of the PHOENIX trial (evaluating planned delivery against expectant management in late preterm preeclampsia) demonstrates that in women who started induction of labour, 63% of women delivered vaginally (56% at 34 weeks’ gestation). Compared to expectant management, planned delivery was associated with higher rates of neonatal unit admission for prematurity (but lower proportions of small-for-gestational age infants); length of neonatal unit stay and neonatal morbidity (including respiratory support) were similar across both intervention groups at all gestational windows. Neonatal unit admission was increased by earlier gestation at delivery, development of severe preeclampsia, and being small-for-gestational age.

Citation

Fleminger, J., Duhig, K., Seed, P. T., Brocklehurst, P., Green, M., Juszczak, E., Marlow, N., Shennan, A., & Chappell, L. (2021). Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial. Pregnancy Hypertension, 26, 91-93. https://doi.org/10.1016/j.preghy.2021.10.002

• Journal Article Type: Article
• Acceptance Date: Oct 11, 2021
• Online Publication Date: Oct 13, 2021
• Publication Date: Dec 1, 2021
• Deposit Date: Oct 22, 2021
• Publicly Available Date: Oct 22, 2021
• Journal: Pregnancy Hypertension
• Print ISSN: 2210-7789
• Electronic ISSN: 2210-7797
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 26
• Pages: 91-93
• DOI: https://doi.org/10.1016/j.preghy.2021.10.002
• Keywords: Obstetrics and Gynaecology; Internal Medicine
• Public URL: https://nottingham-repository.worktribe.com/output/6508145
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S2210778921005250?via%3Dihub