Temporal trends of in utero and early postnatal transfer of extremely preterm infants between 2011 and 2016: a UK population study

Shipley, Lara; Hyliger, Gillian; Sharkey, Don

Abstract

Objective
Early postnatal transfer (PNT) of extremely preterm infants is associated with adverse outcomes compared with in utero transfer (IUT). We aimed to explore recent national trends of IUT and early PNT.

Design
Observational cohort study using the National Neonatal Research Database.

Setting
Neonatal units in England, Scotland and Wales.

Patients
Extremely preterm infants 23+0–27+6 weeks’ gestation admitted for neonatal care from 2011 to 2016.

Main outcome
The incidence of IUT or PNT within 72 hours of life. Secondary outcomes included mortality, hospital transfer level between centres and temporal changes across two equal epochs, 2011–2013 (epoch 1 (Ep1)) and 2014–2016 (epoch 2 (Ep2)).

Results
14 719 infants were included (Ep1=7363 and Ep2=7256); 4005 (27%) underwent IUT; and 3042 (20.7%) had PNT. IUTs decreased significantly between epochs from 28.3% (Ep1=2089) to 26.0% (Ep2=1916) (OR 0.90, 95% CI 0.84 to 0.97, p

Citation

Shipley, L., Hyliger, G., & Sharkey, D. (2022). Temporal trends of in utero and early postnatal transfer of extremely preterm infants between 2011 and 2016: a UK population study. Archives of Disease in Childhood. Fetal and Neonatal Edition, 107(2), 201-205. https://doi.org/10.1136/archdischild-2021-322195

• Journal Article Type: Article
• Acceptance Date: Jul 8, 2021
• Online Publication Date: Jul 19, 2021
• Publication Date: 2022-03
• Deposit Date: Jul 30, 2021
• Publicly Available Date: Jul 30, 2021
• Journal: Archives of Disease in Childhood - Fetal and Neonatal Edition
• Electronic ISSN: 1468-2052
• Publisher: BMJ
• Peer Reviewed: Peer Reviewed
• Volume: 107
• Issue: 2
• Pages: 201-205
• DOI: https://doi.org/10.1136/archdischild-2021-322195
• Keywords: Obstetrics and Gynaecology; General Medicine; Pediatrics, Perinatology, and Child Health
• Public URL: https://nottingham-repository.worktribe.com/output/5817445
• Publisher URL: https://fn.bmj.com/content/early/2021/07/18/archdischild-2021-322195