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Personalization variables in digital mental health interventions for depression and anxiety in adolescents and youth: a scoping review

Wanniarachchi, Vajisha Udayangi; Greenhalgh, Chris; Choi, Adrien; Warren, James R.

Personalization variables in digital mental health interventions for depression and anxiety in adolescents and youth: a scoping review Thumbnail


Authors

Vajisha Udayangi Wanniarachchi

Adrien Choi

James R. Warren



Abstract

Introduction:

The impact of personalization on user engagement and adherence in digital mental health interventions (DMHIs) has been widely explored. However, there is a lack of clarity regarding the prevalence of its application, as well as the dimensions and mechanisms of personalization within DMHIs for adolescents and youth.

Methods:

To understand how personalization has been applied in DMHIs for adolescents and young people, a scoping review was conducted. Empirical studies on DMHIs for adolescents and youth with depression and anxiety, published between 2013 and July 2024, were extracted from PubMed and Scopus. A total of 67 studies were included in the review. Additionally, we expanded an existing personalization framework, which originally classified personalization into four dimensions (content, order, guidance, and communication) and four mechanisms (user choice, provider choice, rulebased, and machine learning), by incorporating non-therapeutic elements.

Results:

The adapted framework includes therapeutic and non-therapeutic content, order, guidance, therapeutic and non-therapeutic communication, interfaces (customization of non-therapeutic visual or interactive components), and interactivity (personalization of user preferences), while retaining the original mechanisms. Half of the interventions studied used only one personalization dimension (51%), and more than two-thirds used only one personalization mechanism. This review found that personalization of therapeutic content (51% of the interventions) and interfaces (25%) were favored. User choice was the most prevalent personalization mechanism, present in 60% of interventions. Additionally, machine learning mechanisms were employed in a substantial number of cases (30%), but there were no instances of generative artificial intelligence (AI) among the included studies.

Discussion:

The findings of the review suggest that although personalization elements of the interventions are reported in the articles, their impact on younger people’s experience with DMHIs and adherence to mental health protocols is not thoroughly addressed. Future interventions may benefit from incorporating generative AI, while adhering to standard clinical research practices, to further personalize user experiences.

Citation

Wanniarachchi, V. U., Greenhalgh, C., Choi, A., & Warren, J. R. (2025). Personalization variables in digital mental health interventions for depression and anxiety in adolescents and youth: a scoping review. Frontiers in Digital Health, 7, Article 1500220. https://doi.org/10.3389/fdgth.2025.1500220

Journal Article Type Article
Acceptance Date Apr 30, 2025
Online Publication Date May 15, 2025
Publication Date May 15, 2025
Deposit Date Jun 27, 2025
Publicly Available Date Jun 30, 2025
Journal Frontiers in Digital Health
Electronic ISSN 2673-253X
Publisher Frontiers Media
Peer Reviewed Peer Reviewed
Volume 7
Article Number 1500220
DOI https://doi.org/10.3389/fdgth.2025.1500220
Keywords personalisation, digital mental health interventions, adolescents, youth, anxiety, depression, adherence
Public URL https://nottingham-repository.worktribe.com/output/50717256
Publisher URL https://www.frontiersin.org/journals/digital-health/articles/10.3389/fdgth.2025.1500220/full

Files

Fdgth-1-1500220 (1.6 Mb)
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/

Copyright Statement
Copyright: © 2025 Wanniarachchi, Greenhalgh, Choi and Warren. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.





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