Antimicrobial resistance: Concerns of healthcare providers and people with CF

Bullington, Wendy; Hempstead, Sarah; Smyth, Alan R.; Drevinek, Pavel; Saiman, Lisa; Waters, Valerie J.; Bell, Scott C.; VanDevanter, Donald R.; Flume, Patrick A.; Elborn, Stuart; Muhlebach, Marianne S.; Antimicrobial Resistance International Working Group in Cystic Fibrosis

Abstract

Background
Chronic lung infections and their treatment pose risks for the development of antimicrobial resistance (AMR) in people with cystic fibrosis (PWCF). In this study, we evaluated the attitudes of healthcare providers’ (HCP) and PWCF or their parents’ toward AMR within the international CF community.

Methods
HCP and PWCF identified through listservs and CF-related organizations were asked to complete an AMR centered survey, with additional questions on antimicrobial stewardship (AMS) for HCP. Descriptive analyses are reported.

Results
The responding 443 HCP and 464 PWCF/Parents were from 30 and 25 countries, respectively. Sixty-two percent of HCP and 56% of PWCF stated they were “very concerned” about AMR, with Pseudomonas spp. and Burkholderia spp. considered the most concerning organisms for both HCP and PWCF/Parents. Non-tuberculous mycobacteria were of greater concern to HCP compared to PWCF/Parents. There was a discrepancy regarding AMR education to PWCF, with 80% of HCP stating having discussed this with PWCF/Parents, but only 50% of PWCF recalling such discussions.

Conclusion
These results highlight that AMR is relevant to CF HCP and PWCF internationally, indicating that educational tools and research are warranted.

Citation

Bullington, W., Hempstead, S., Smyth, A. R., Drevinek, P., Saiman, L., Waters, V. J., Bell, S. C., VanDevanter, D. R., Flume, P. A., Elborn, S., Muhlebach, M. S., & Antimicrobial Resistance International Working Group in Cystic Fibrosis. (2021). Antimicrobial resistance: Concerns of healthcare providers and people with CF. Journal of Cystic Fibrosis, 20(3), 407-412. https://doi.org/10.1016/j.jcf.2020.05.009

• Journal Article Type: Article
• Acceptance Date: May 27, 2020
• Online Publication Date: Jun 17, 2020
• Publication Date: 2021-05
• Deposit Date: Jun 21, 2020
• Publicly Available Date: Jun 18, 2021
• Journal: Journal of Cystic Fibrosis
• Print ISSN: 1569-1993
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 20
• Issue: 3
• Pages: 407-412
• DOI: https://doi.org/10.1016/j.jcf.2020.05.009
• Keywords: Pediatrics, Perinatology, and Child Health; Pulmonary and Respiratory Medicine
• Public URL: https://nottingham-repository.worktribe.com/output/4693313
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S1569199320301594