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Age‐related decrements in cortical gyrification: Evidence from an accelerated longitudinal dataset

Madan, Christopher R.

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Abstract

Cortical gyrification has been found to decrease due to aging, but thus far this has only been examined in cross‐sectional samples. Interestingly, the topography of these age‐related differences in gyrification follows a distinct gradient along the cortex relative to age effects on cortical thickness, likely suggesting a different underlying neurobiological mechanism. Here I examined several aspects of gyrification in an accelerated longitudinal dataset of 280 healthy adults aged 45–92 with an interval between first and last MRI sessions of up to 10 years (total of 815 MRI sessions). Results suggest that age changes in sulcal morphology underlie these changes in gyrification.

Citation

Madan, C. R. (2021). Age‐related decrements in cortical gyrification: Evidence from an accelerated longitudinal dataset. European Journal of Neuroscience, 53(5), 1661-1671. https://doi.org/10.1111/ejn.15039

Journal Article Type Article
Acceptance Date Oct 31, 2020
Online Publication Date Nov 23, 2020
Publication Date 2021-03
Deposit Date Nov 1, 2020
Publicly Available Date Nov 24, 2021
Journal European Journal of Neuroscience
Print ISSN 0953-816X
Electronic ISSN 1460-9568
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 53
Issue 5
Pages 1661-1671
DOI https://doi.org/10.1111/ejn.15039
Public URL https://nottingham-repository.worktribe.com/output/4106485
Publisher URL https://onlinelibrary.wiley.com/doi/10.1111/ejn.15039
Additional Information This is the peer reviewed version of the following article: Madan, CR. Age‐related decrements in cortical gyrification: Evidence from an accelerated longitudinal dataset. Eur J Neurosci. 2020, which has been published in final form at https://doi.org/10.1111/ejn.15039. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.

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