PLA/chitosan/keratin composites for biomedical applications

Tanase, Constantin Edi; Spiridon, Iuliana

Abstract

Novel composites based on PLA, chitosan and keratin was obtained via blend preparation. The goal of this contribution was to evaluate mechanical and in vitro behavior of the composites. The results point out composites with improved Young modulus and decreased tensile strength, significant increase in hardness (compared to PLA) and a good uptake of the surface properties. Biological assessments using human osteosarcoma cell line on these composites indicate a good viability/proliferation outcome. Hence preliminary results regarding mechanical behavior and in vitro osteoblast response suggest that these composites might have prospective application in medical field.

Citation

Tanase, C. E., & Spiridon, I. (2014). PLA/chitosan/keratin composites for biomedical applications. Materials Science and Engineering: C, 40, 242-247. https://doi.org/10.1016/j.msec.2014.03.054

• Journal Article Type: Article
• Acceptance Date: Mar 21, 2014
• Online Publication Date: Mar 31, 2014
• Publication Date: Jul 1, 2014
• Deposit Date: Apr 16, 2021
• Journal: Materials Science and Engineering: C
• Print ISSN: 0928-4931
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 40
• Pages: 242-247
• DOI: https://doi.org/10.1016/j.msec.2014.03.054
• Keywords: PLAChitosanKeratinBiomaterialsMechanical propertiesIn vitro studies
• Public URL: https://nottingham-repository.worktribe.com/output/3961674
• Publisher URL: http://www.sciencedirect.com/science/article/pii/S0928493114001805