Strategies for producing high value small molecules in microalgae

O'Neill, Ellis; Cagney, Michael

Abstract

Eukaryotic microalgae are a diverse group of organisms that can be used for the sustainable production of a wide range of high value compounds, including lipids, flavours and colourants, bioplastics and cosmetics. Optimising total biomass production often does not lead to optimal product yield and more sophisticated biphasic growth strategies are needed, introducing specific stresses to induce product synthesis. Genetic tools have been used to increase yields of natural products or to introduce new pathways to algae, and wider deployment of these tools offers promising routes for commercial production of high value compounds utilising minimal inputs.

Citation

O'Neill, E., & Cagney, M. (2024). Strategies for producing high value small molecules in microalgae. Plant Physiology and Biochemistry, 214, Article 108942. https://doi.org/10.1016/j.plaphy.2024.108942

• Journal Article Type: Article
• Acceptance Date: Jul 15, 2024
• Online Publication Date: Jul 16, 2024
• Publication Date: 2024-09
• Deposit Date: Sep 10, 2024
• Publicly Available Date: Sep 11, 2024
• Journal: Plant Physiology and Biochemistry
• Print ISSN: 0981-9428
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 214
• Article Number: 108942
• DOI: https://doi.org/10.1016/j.plaphy.2024.108942
• Keywords: high value products; algal biotechnology; microalgae; mycosporine-like amino acids; terpenes; polyhydroxyalkanoates; metabolic engineering
• Public URL: https://nottingham-repository.worktribe.com/output/37307674
• Publisher URL: https://www.sciencedirect.com/science/article/pii/S0981942824006107?via%3Dihub