The genomic mosaicism of hybrid speciation

Elgvin, Tore O.; Trier, Cassandra N.; T�rresen, Ole K.; Hagen, Ingerid J.; Lien, Sigbj�rn; Nederbragt, Alexander J.; Ravinet, Mark; Jensen, Henrik; S�tre, Glenn Peter

Abstract

Copyright © 2017 The Authors, some rights reserved. Hybridization is widespread in nature and, in some instances, can result in the formation of a new hybrid species. We investigate the genetic foundation of this poorly understood process through whole-genome analysis of the hybrid Italian sparrow and its progenitors. We find overall balanced yet heterogeneous levels of contribution from each parent species throughout the hybrid genome and identify areas of novel divergence in the hybrid species exhibiting signals consistent with balancing selection. High-divergence areas are disproportionately located on the Z chromosome and overrepresented in gene networks relating to key traits separating the focal species, which are likely involved in reproductive barriers and/or species-specific adaptations. Of special interest are genes and functional groups known to affect body patterning, beak morphology, and the immune system, which are important features of diversification and fitness. We show that a combination of mosaic parental inheritance and novel divergence within the hybrid lineage has facilitated the origin and maintenance of an avian hybrid species.

Citation

Elgvin, T. O., Trier, C. N., Tørresen, O. K., Hagen, I. J., Lien, S., Nederbragt, A. J., Ravinet, M., Jensen, H., & Sætre, G. P. (2017). The genomic mosaicism of hybrid speciation. Science Advances, 3(6), Article e1602996. https://doi.org/10.1126/sciadv.1602996

• Journal Article Type: Article
• Acceptance Date: Apr 26, 2017
• Online Publication Date: Jun 14, 2017
• Publication Date: Jun 2, 2017
• Deposit Date: Jan 14, 2020
• Publicly Available Date: Jan 17, 2020
• Journal: Science Advances
• Electronic ISSN: 2375-2548
• Publisher: American Association for the Advancement of Science
• Peer Reviewed: Peer Reviewed
• Volume: 3
• Issue: 6
• Article Number: e1602996
• DOI: https://doi.org/10.1126/sciadv.1602996
• Public URL: https://nottingham-repository.worktribe.com/output/3725820
• Publisher URL: https://advances.sciencemag.org/content/3/6/e1602996