Estimation of Conductivity Tensors from Human Ventricular Optical Mapping Recordings

Walmsley, John; Mirams, Gary R.; Efimov, Igor R.; Burrage, Kevin; Rodriguez, Blanca

Abstract

Experimental recordings of transmural activation in the human left ventricle show variability in recorded activation times. In this paper we demonstrate a framework for fitting the conductivity tensor of a monodomain model to reproduce activation times for an individual experiment whilst taking into account uncertainty in the fibre orientation. By directly registering anatomical features onto the difference between simulated and experimental results, we are then able to identify structural heterogeneities which impact on conduction in the left ventricle. © 2013 Springer-Verlag.

Citation

Walmsley, J., Mirams, G. R., Efimov, I. R., Burrage, K., & Rodriguez, B. (2013). Estimation of Conductivity Tensors from Human Ventricular Optical Mapping Recordings. In S. Ourselin, D. Rueckert, & N. Smith (Eds.), Functional Imaging and Modeling of the Heart: 7th International Conference, FIMH 2013, London, UK, June 20-22, 2013. Proceedings (224-231). Springer Verlag. https://doi.org/10.1007/978-3-642-38899-6_27

• Publication Date: 2013
• Deposit Date: Jan 14, 2020
• Publisher: Springer Verlag
• Pages: 224-231
• Series Title: Lecture Notes in Computer Science
• Series Number: 7945
• Book Title: Functional Imaging and Modeling of the Heart: 7th International Conference, FIMH 2013, London, UK, June 20-22, 2013. Proceedings
• ISBN: 9783642388989
• DOI: https://doi.org/10.1007/978-3-642-38899-6_27
• Public URL: https://nottingham-repository.worktribe.com/output/3217520
• Publisher URL: https://link.springer.com/chapter/10.1007/978-3-642-38899-6_27