Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study

Muthuri, Stella G.; Zhang, Weiya; Maciewicz, Rose A.; Muir, Kenneth; Doherty, Michael

Abstract

© 2015 Muthuri et al.; licensee BioMed Central. Introduction: The aim of this study was to investigate the association between alcoholic and non-alcoholic beverages and knee or hip osteoarthritis (OA). Methods: We conducted a case-control study of Caucasian men and women aged 45 to 86 years of age from Nottingham, UK. Cases had clinically severe symptoms and radiographic knee or hip OA; controls had no symptoms and no radiographic knee or hip OA. Exposure information was sought using interview-based questionnaires and a semi-quantitative food frequency questionnaire to assess beverage consumption at ages 21 to 50 years. Odds ratios (ORs), adjusted ORs (aORs), 95% confidence intervals (CI) and P values were estimated using logistic regression models. Results: A total of 1,001 knee OA, 993 hip OA and 933 control participants were included in the study. Increasing beer consumption was associated with an increasing risk of OA (P for trend ≤ 0.001). Compared to those who did not consume beer, aORs for people who consumed 20 or more servings of beer were 1.93 (95% CI 1.26 to 2.94) and 2.15 (95% CI 1.45 to 3.19) for knee OA and hip OA, respectively. In contrast, increasing levels of wine consumption were associated with decreased likelihood of knee OA (P for trend

Citation

Muthuri, S. G., Zhang, W., Maciewicz, R. A., Muir, K., & Doherty, M. (2015). Beer and wine consumption and risk of knee or hip osteoarthritis: a case control study. Arthritis Research and Therapy, 17(1), 23. https://doi.org/10.1186/s13075-015-0534-4

• Journal Article Type: Article
• Acceptance Date: Jan 21, 2015
• Online Publication Date: Feb 5, 2015
• Publication Date: Feb 5, 2015
• Deposit Date: Nov 26, 2019
• Journal: Arthritis Research & Therapy
• Print ISSN: 1478-6354
• Electronic ISSN: 1478-6362
• Publisher: BioMed Central
• Peer Reviewed: Peer Reviewed
• Volume: 17
• Issue: 1
• Pages: 23
• DOI: https://doi.org/10.1186/s13075-015-0534-4
• Public URL: https://nottingham-repository.worktribe.com/output/3086481