Feedback control in hemodialysis

Randhay, Ashveer; Tarek Eldehni, Mohamed; Selby, Nicholas M.

Abstract

A number of systems of feedback control during dialysis have been developed, which have the shared characteristic of prospectively measuring physiological parameters and then automatically altering dialysis parameters in real time according to a pre-specified dialysis prescription. These include feedback systems aimed at reducing intradialytic hypotension based on relative blood volume monitoring linked to adjustments in ultrafiltration and dialysate conductivity, and blood temperature monitoring linked to alterations in dialysate temperature. Feedback systems also exist that manipulate sodium balance during dialysis by assessing and adjusting dialysate conductivity. In this review article, we discuss the rationale for automated feedback systems during dialysis, describe how the different feedback systems work, and provide a review of the current evidence on their clinical effectiveness.

Citation

Randhay, A., Tarek Eldehni, M., & Selby, N. M. (2023). Feedback control in hemodialysis. Seminars in Dialysis, https://doi.org/10.1111/sdi.13185

• Journal Article Type: Article
• Acceptance Date: Oct 23, 2023
• Online Publication Date: Nov 23, 2023
• Publication Date: Nov 23, 2023
• Deposit Date: Mar 26, 2024
• Publicly Available Date: Apr 9, 2024
• Journal: Seminars in Dialysis
• Print ISSN: 0894-0959
• Electronic ISSN: 1525-139X
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1111/sdi.13185
• Public URL: https://nottingham-repository.worktribe.com/output/27600575
• Publisher URL: https://onlinelibrary.wiley.com/doi/10.1111/sdi.13185