Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial

Chappell, Lucy C; Bell, Jennifer L; Smith, Anne; Linsell, Louise; Juszczak, Edmund; Dixon, Peter H; Chambers, Jenny; Hunter, Rachael; Dorling, Jon; Williamson, Catherine; Thornton, Jim G; Ahmed, Irshad; Arya, Rita; Beckett, Virginia; Bhide, Amarnath; Brown, Heather; Bugg, George; Cameron, Helen; Deole, Nishigandh; Dey, Madhuchanda; Dwyer, James; Fahel, Leila; Gada, Ruta; Girling, Joanna; Haestier, Anna; Hughes, Sean; Indusekhar, Radha; Jones, Bryony; Khan, Rahila; Kirkpatrick, Alison; Knox, Ellen; Lincoln, Karen; MacDougall, Malcolm; Majoko, Franz; McIntyre, Karen; Noori, Muna; Oakley, Wendy; Preston, Jane; Ranka, Poornima; Rashid, Mumtaz; Salloum, Marwan; Samyraju, Manjula; Schram, Catharina; Sen, Seema; Stone, Sophia; Tan, Bee

doi:10.1016/s0140-6736(19)31270-x

Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial

Chappell, Lucy C; Bell, Jennifer L; Smith, Anne; Linsell, Louise; Juszczak, Edmund; Dixon, Peter H; Chambers, Jenny; Hunter, Rachael; Dorling, Jon; Williamson, Catherine; Thornton, Jim G; Ahmed, Irshad; Arya, Rita; Beckett, Virginia; Bhide, Amarnath; Brown, Heather; Bugg, George; Cameron, Helen; Deole, Nishigandh; Dey, Madhuchanda; Dwyer, James; Fahel, Leila; Gada, Ruta; Girling, Joanna; Haestier, Anna; Hughes, Sean; Indusekhar, Radha; Jones, Bryony; Khan, Rahila; Kirkpatrick, Alison; Knox, Ellen; Lincoln, Karen; MacDougall, Malcolm; Majoko, Franz; McIntyre, Karen; Noori, Muna; Oakley, Wendy; Preston, Jane; Ranka, Poornima; Rashid, Mumtaz; Salloum, Marwan; Samyraju, Manjula; Schram, Catharina; Sen, Seema; Stone, Sophia; Tan, Bee

Authors

Lucy C Chappell

Jennifer L Bell

Anne Smith

Louise Linsell

Professor ED JUSZCZAK ED.JUSZCZAK@NOTTINGHAM.AC.UK
Professor of Clinical Trials and Statistics in Medicine

Peter H Dixon

Jenny Chambers

Rachael Hunter

Jon Dorling

Catherine Williamson

Jim G Thornton

Irshad Ahmed

Rita Arya

Virginia Beckett

Amarnath Bhide

Heather Brown

George Bugg

Helen Cameron

Nishigandh Deole

Madhuchanda Dey

James Dwyer

Leila Fahel

Ruta Gada

Joanna Girling

Anna Haestier

Sean Hughes

Radha Indusekhar

Bryony Jones

Rahila Khan

Alison Kirkpatrick

Ellen Knox

Karen Lincoln

Malcolm MacDougall

Franz Majoko

Karen McIntyre

Muna Noori

Wendy Oakley

Jane Preston

Poornima Ranka

Mumtaz Rashid

Marwan Salloum

Manjula Samyraju

Catharina Schram

Seema Sen

Sophia Stone

Bee Tan

Citation

Chappell, L. C., Bell, J. L., Smith, A., Linsell, L., Juszczak, E., Dixon, P. H., …Tan, B. (2019). Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet, 394(10201), 849-860. https://doi.org/10.1016/s0140-6736%2819%2931270-x

Journal Article Type	Article
Acceptance Date	Jul 1, 2019
Online Publication Date	Aug 1, 2019
Publication Date	2019-09
Deposit Date	Sep 24, 2019
Publicly Available Date	Sep 24, 2019
Journal	The Lancet
Print ISSN	0140-6736
Electronic ISSN	1474-547X
Publisher	Elsevier
Peer Reviewed	Peer Reviewed
Volume	394
Issue	10201
Pages	849-860
DOI	https://doi.org/10.1016/s0140-6736%2819%2931270-x
Keywords	General Medicine
Public URL	https://nottingham-repository.worktribe.com/output/2655271
Publisher URL	https://www.sciencedirect.com/science/article/pii/S014067361931270X
Additional Information	Date of acceptance estimated. This article is maintained by: Elsevier; Article Title: Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial; Journal Title: The Lancet; CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/S0140-6736(19)31270-X; CrossRef DOI link to the associated document: https://doi.org/10.1016/S0140-6736(19)31607-1; Content Type: article; Copyright: © 2019 The Author(s). Published by Elsevier Ltd.
Contract Date	Sep 24, 2019