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Multi-level community interventions for primary stroke prevention: A conceptual approach by the World Stroke Organization

Brainin, Michael; Feigin, Valery; Bath, Philip M; Collantes, Epifania; Martins, Sheila; Pandian, Jeyaraj; Sacco, Ralph; Teuschl, Yvonne

Multi-level community interventions for primary stroke prevention: A conceptual approach by the World Stroke Organization Thumbnail


Authors

Michael Brainin

Valery Feigin

PHILIP BATH philip.bath@nottingham.ac.uk
Stroke Association Professor of Stroke Medicine

Epifania Collantes

Sheila Martins

Jeyaraj Pandian

Ralph Sacco

Yvonne Teuschl



Abstract

The increasing burden of stroke and dementia emphasizes the need for new, well-tolerated and cost-effective primary prevention strategies that can reduce the risks of stroke and dementia worldwide, and specifically in low- and middle-income countries (LMICs).

 This paper outlines conceptual frameworks of three primary stroke prevention strategies: (a) the “polypill” strategy; (b) a “population-wide” strategy; and (c) a “motivational population-wide” strategy.

 (a) A polypill containing generic low-dose ingredients of blood pressure and lipid-lowering medications (e.g. candesartan 16 mg, amlodipine 2.5 mg, and rosuvastatin 10 mg) seems a safe and cost-effective approach for primary prevention of stroke and dementia.

 (b) A population-wide strategy reducing cardiovascular risk factors in the whole population, regardless of the level of risk is the most effective primary prevention strategy. A motivational population-wide strategy for the modification of health behaviors (e.g. smoking, diet, physical activity) should be based on the principles of cognitive behavioral therapy. Mobile technologies, such as smartphones, offer an ideal interface for behavioral interventions (e.g. Stroke Riskometer app) even in LMICs.

 (c) Community health workers can improve the maintenance of lifestyle changes as well as the adherence to medication, especially in resource poor areas. An adequate training of community health workers is a key point.

Citation

Brainin, M., Feigin, V., Bath, P. M., Collantes, E., Martins, S., Pandian, J., …Teuschl, Y. (2019). Multi-level community interventions for primary stroke prevention: A conceptual approach by the World Stroke Organization. International Journal of Stroke, 14(8), 818-825. https://doi.org/10.1177/1747493019873706

Journal Article Type Article
Acceptance Date Jun 13, 2019
Online Publication Date Sep 9, 2019
Publication Date Sep 9, 2019
Deposit Date Sep 12, 2019
Publicly Available Date Sep 12, 2019
Journal International Journal of Stroke
Print ISSN 1747-4930
Electronic ISSN 1747-4949
Publisher SAGE Publications
Peer Reviewed Peer Reviewed
Volume 14
Issue 8
Pages 818-825
DOI https://doi.org/10.1177/1747493019873706
Keywords Neurology
Public URL https://nottingham-repository.worktribe.com/output/2607926
Publisher URL https://journals.sagepub.com/doi/10.1177/1747493019873706
Contract Date Sep 12, 2019

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