Comprehensive Geriatric Assessment for Older Women with Early-Stage (Non-Metastatic) Breast Cancer—An Updated Systematic Review of the Literature

Reid-Agboola, Chantae; Klukowska, Anita; Malcolm, Francesca L.; Harrison, Cora; Parks, Ruth M.; Cheung, Kwok-Leung

Abstract

Background: A previous systematic review by our team (2012) undertook comprehensive geriatric assessment (CGA) in breast cancer and concluded there was not sufficient evidence to instate CGA as mandatory practice. SIOG/EUSOMA guidelines published in 2021 advocate the use of CGA in breast cancer patients. The aim is to perform an updated systematic review of the literature. Methods: A systematic review of studies published between 2012 and 2022 that assessed the use of CGA in breast cancer was performed on Cochrane, PubMed and Embase. Results: A total of 18 articles including 4734 patients with breast cancer were identified. The studies covered four themes for use of CGA in breast cancer: (1) to determine factors influencing survival (2) as an adjunct to treatment decision-making (3) to measure quality of life, and (4) to determine which tools should be included. There was evidence to support the use of CGA in themes 1–3; however, it is uncertain which assessment tools are best to use (theme 4). Conclusions: CGA can be used to determine factors affecting survival and quality of life in breast cancer patients and can therefore be used to aid treatment decision-making. Further work is required to determine gold standard CGA.

Citation

Reid-Agboola, C., Klukowska, A., Malcolm, F. L., Harrison, C., Parks, R. M., & Cheung, K.-L. (2023). Comprehensive Geriatric Assessment for Older Women with Early-Stage (Non-Metastatic) Breast Cancer—An Updated Systematic Review of the Literature. Current Oncology, 30(9), 8294-8309. https://doi.org/10.3390/curroncol30090602

• Journal Article Type: Review
• Acceptance Date: Sep 7, 2023
• Online Publication Date: Sep 7, 2023
• Publication Date: 2023-09
• Deposit Date: Oct 25, 2023
• Publicly Available Date: Oct 25, 2023
• Journal: Current Oncology
• Print ISSN: 1718-7729
• Electronic ISSN: 1718-7729
• Publisher: MDPI
• Peer Reviewed: Peer Reviewed
• Volume: 30
• Issue: 9
• Pages: 8294-8309
• DOI: https://doi.org/10.3390/curroncol30090602
• Keywords: Comprehensive geriatric assessment; breast cancer; primary; operable
• Public URL: https://nottingham-repository.worktribe.com/output/25081906